Investigating the dose-response relation between air pollution and total mortality in the APHEA-2 multicity project (Publications)
BACKGROUND: Several recent studies have reported significant health effects of air pollution even at low levels of air pollutants, but in most of these studies linear non-threshold relations were assu
Population sampling in European air pollution exposure study, EXPOLIS: comparisons between the cities and representativeness of the samples (Publications)
A personal air pollution exposure study, EXPOLIS, was accomplished in six European cities among 25- to 55-year-old citizens. In order to compare the exposure results and different microenvironmental c
Human health benefits from livestock vaccination for brucellosis: case study (Publications)
OBJECTIVE: To estimate the economic benefit, cost-effectiveness, and distribution of benefit of improving human health in Mongolia through the control of brucellosis by mass vaccination of livestock.
Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin (Publications)
In two steps from dihydroartemisinin, a small array of 16 semisynthetic C-10 pyrrole Mannich artemisinin derivatives (7a-p) have been prepared in moderate to excellent yield. In vitro analysis against
Does radical cure of asymptomatic <em>Plasmodium falciparum</em> place adults in endemic areas at increased risk of recurrent symptomatic malaria? (Publications)
A cohort of 197 adults in Kassena-Nankana District (northern Ghana) was radically cured of malaria parasites to study subsequent incidence of malaria infection. During the following 20 weeks of the ma
Malaria vaccine candidate: design of a multivalent subunit alpha-helical coiled coil poly-epitope (Publications)
A new strategy for the rapid identification of new malaria antigens based on protein structural motifs was previously described. We identified and evaluated the malaria vaccine potential of fragments
Contribution of influenza immunity and virosomal-formulated synthetic peptide to cellular immune responses in a phase I subunit malaria vaccine trial (Publications)
We have demonstrated recently in a phase Ia clinical trial that synthetic malaria peptides delivered by immuno-potentiating reconstituted influenza virosomes (IRIV) induced long-lived peptide-specific
Malaria-infected mice are cured by oral administration of new artemisinin derivatives (Publications)
In four or five chemical steps from the 1,2,4-trioxane artemisinin, a new series of 23 trioxane dimers has been prepared. Eleven of these new trioxane dimers cure malaria-infected mice via oral dosing
Global goods movement and the local burden of childhood asthma in southern California (Publications)
OBJECTIVES: As part of a community-based participatory research effort, we estimated the preventable burden of childhood asthma associated with air pollution in the southern California communities of