<em>In vitro</em>, <em>ex vivo</em> and<em> in vivo</em> activity of diamidines against <em>Trypanosoma congolense</em> and <em>Trypanosoma vivax</em> (Publications)
African Animal Trypanosomosis (AAT) is caused by the tsetse-transmitted protozoans, Trypanosoma congolense and T. vivax, leading to huge agricultural losses throughout sub-Saharan Africa. Three drugs
An investment case to prevent the reintroduction of malaria in Sri Lanka (Publications)
Sri Lanka has made remarkable gains in reducing the burden of malaria, recording no locally transmitted malaria cases since November 2012 and zero deaths since 2007. The country was recently certified
Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa (Publications)
OBJECTIVE: To estimate time from HIV infection to linkage-to-care and its determinants. Linkage-to-care is usually assessed using the date of HIV diagnosis as the starting point for exposure time. How
Clinical markers of asthma and IgE assessed in parents before conception predicts asthma and hay fever in the offspring (Publications)
BACKGROUND: Mice models suggest epigenetic inheritance induced by parental allergic disease activity. However, we know little of how parental disease activity before conception influences offspring's
Time to harmonize national ambient air quality standards (Publications)
OBJECTIVES: The World Health Organization has developed ambient air quality guidelines at levels considered to be safe or of acceptable risk for human health. These guidelines are meant to support gov
Unmasking inequalities: sub-national maternal and child mortality data from two urban slums in Lagos, Nigeria tells the story (Publications)
INTRODUCTION: Nigeria has one of the highest maternal mortality ratios in the world as well as high perinatal mortality. Unfortunately, the country does not have the resources to assess this critical
Structure and biosynthesis of isatropolones, bioactive amine-scavenging fluorescent natural products from <em>streptomyces Go66</em> (Publications)
The natural products isatropolone A-C (1-3) were reisolated from Streptomyces Go66, with 1 and 3 showing potent activity against Leishmania donovani. They contain a rare tropolone ring derived from a