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1. Exposure of <em>Heligmosomoides polygyrus</em> and <em>Trichuris muris</em> to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate... (Publications)

   Exposure of <em>Heligmosomoides polygyrus</em> and <em>Trichuris muris</em> to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate <em>in vitro</em> and <em>in vivo</em> to elucidate the pathway of drug entry into these gastrointestinal ne

   Relevance:

   Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug

2. Global health financing towards 2030 and beyond (Publications)

   Global health financing towards 2030 and beyond

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3. Predictive malaria epidemiology: modeling malaria infection dynamics and impact of control interventions (Publications)

   Predictive malaria epidemiology: modeling malaria infection dynamics and impact of control interventions

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4. Monitoring of selected health indicators in children living in a copper mine development area in northwestern Zambia (Publications)

   Monitoring of selected health indicators in children living in a copper mine development area in northwestern Zambia

   Relevance:

   The epidemiology of malaria, anaemia and malnutrition in children is potentially altered in mining development areas. In a copper extraction project in northwestern Zambia, a health impact assessment

5. Low efficacy of albendazole against <em>Trichuris trichiura</em> infection in schoolchildren from Port Elizabeth, South Africa (Publications)

   Low efficacy of albendazole against <em>Trichuris trichiura</em> infection in schoolchildren from Port Elizabeth, South Africa

   Relevance:

   BACKGROUND: Albendazole is one of two standard drugs for the control of soil-transmitted helminthiasis. METHODS: A total of 149 schoolchildren from Port Elizabeth, South Africa, were examined for soil

6. Antimalarial pyrido[1,2-a]benzimidazoles: lead optimization, parasite life cycle stage profile, mechanistic evaluation, killing kinetics, and <em>in... (Publications)

   Antimalarial pyrido[1,2-a]benzimidazoles: lead optimization, parasite life cycle stage profile, mechanistic evaluation, killing kinetics, and <em>in vivo</em> oral efficacy in a mouse model

   Relevance:

   Further structure-activity relationship (SAR) studies on the recently identified pyrido[1,2-a]benzimidazole (PBI) antimalarials have led to the identification of potent, metabolically stable compounds

7. Controlling schistosomiasis with praziquantel: how much longer without a viable alternative? (Publications)

   Controlling schistosomiasis with praziquantel: how much longer without a viable alternative?

   Relevance:

   The current approach of morbidity control of schistosomiasis, a helminth disease of poverty with considerable public health and socioeconomic impact, is based on preventive chemotherapy with praziquan

8. False-negative malaria rapid diagnostic tests in Rwanda: impact of <em>Plasmodium falciparum</em> isolates lacking <em>hrp2</em> and declining malaria... (Publications)

   False-negative malaria rapid diagnostic tests in Rwanda: impact of <em>Plasmodium falciparum</em> isolates lacking <em>hrp2</em> and declining malaria transmission

   Relevance:

   BACKGROUND: Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are often used to determine whether persons with fever should be treated with anti-malarials. However, Plasmodium falcipar

9. Operational and implementation research within Global Fund to Fight AIDS, Tuberculosis and Malaria grants: a situation analysis in six countries (Publications)

   Operational and implementation research within Global Fund to Fight AIDS, Tuberculosis and Malaria grants: a situation analysis in six countries

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10. A switch in regulatory T cells through farm-exposure during immune maturation in childhood (Publications)

    A switch in regulatory T cells through farm-exposure during immune maturation in childhood

    Relevance:

    BACKGROUND: Farm exposure protects against development of allergies early in life. At 4.5 years, protection against asthma by farm-milk exposure was partially mediated by regulatory T-cells (Tregs). T