Direct susceptibility testing of <em>Mycobacterium tuberculosis</em> for pyrazinamide using the BACTEC MGIT 960 system (Publications)
Pyrazinamide is a key antituberculosis drug, yet no rapid susceptibility test is commercially available. PZA drug susceptibility testing (DST) was performed directly on the sputum from 327 patients an
Comparative performance of three experimental hut designs for measuring malaria vector responses to insecticides in Tanzania (Publications)
BACKGROUND: Experimental huts are simplified, standardized representations of human habitations that provide model systems to evaluate insecticides used in indoor residual spray (IRS) and long-lasting
Evolution of the national schistosomiasis control programmes in the People's Republic of China (Publications)
Schistosomiasis japonica is caused by the parasitic trematode Schistosoma japonicum. It is endemic in The People's Republic of China and has significant impact on human health and socioeconomic develo
Dog demography, animal bite management and rabies knowledge-attitude and practices in the Awash Basin, eastern Ethiopia (Publications)
BACKGROUND: Rabies is a viral zoonosis that has been described in limited numbers of studies in Ethiopia at large and among pastoralists in particular. This study assessed dog demography, bite wound p
Alkanediamide-linked bisbenzamidines are promising antiparasitic agents (Publications)
A series of 15 alkanediamide-linked bisbenzamidines and related analogs was synthesized and tested in vitro against two Trypanosoma brucei (T.b.) subspecies: T.b. brucei and T.b. rhodesiense, Trypanos
Extremely low-frequency magnetic fields and risk of childhood leukemia: a risk assessment by the ARIMMORA consortium (Publications)
Exposure to extremely low-frequency magnetic fields (ELF-MF) was evaluated in an International Agency for Research on Cancer (IARC) Monographs as "possibly carcinogenic to humans" in 2001, based on in
Public health impacts of city policies to reduce climate change: findings from the URGENCHE EU-China project (Publications)
BACKGROUND: Climate change is a global threat to health and wellbeing. Here we provide findings of an international research project investigating the health and wellbeing impacts of policies to reduc
Identification of new human malaria parasite <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase inhibitors by pharmacophore and... (Publications)
Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH), a key enzyme in the de novo pyrimidine biosynthesis pathway, which the Plasmodium falciparum relies on exclusively for survival, has emerg
Bimodal X-ray and infrared imaging of an organometallic derivative of praziquantel in <em>Schistosoma mansoni</em> (Publications)
An organometallic derivative of praziquantel was studied directly in worms, using ICP-MS for quantification and synchrotron based imaging. X-Ray fluorescence and IR absorption microspectroscopy, were
