Large-scale determinants of intestinal schistosomiasis and intermediate host snail distribution across Africa: does climate matter? (Publications)
The geographical ranges of most species, including many infectious disease agents and their vectors and intermediate hosts, are assumed to be constrained by climatic tolerances, mainly temperature. It
Asthma score: predictive ability and risk factors (Publications)
BACKGROUND: Definition of asthma as a continuous score is a promising tool for population studies that has not yet been fully evaluated. OBJECTIVE: We assessed (i) the predictive ability of an asthma
Exposure to a farming environment has allergen-specific protective effects on T(H)2-dependent isotype switching in response to common inhalants (Publications)
BACKGROUND: IgE synthesis by human B cells results from allergen-dependent, T(H)2-mediated isotype switching. Exposure to a farming environment protects against IgE responses. OBJECTIVE: We reconstruc
Structural and functional characterisation of the toll like receptor 9 of <em>Aotus nancymaae</em>, a non-human primate model for malaria vaccine... (Publications)
In the absence of suitable rodent animal models for Plasmodium falciparum malaria, the efficacy testing of asexual blood-stage vaccine candidates in Aotus nancymaae represents a tool to select between
Micro-scale investigation of intestinal schistosomiasis transmission on Ngamba and Kimi islands, Lake Victoria, Uganda (Publications)
A study to investigate the effect of environmental predictors on abundance of Biomphalaria, the intermediate host snails of Schistosoma mansoni, was carried out on two small islands in Lake Victoria,
Cytochrome P450 6M2 from the malaria vector <em>Anopheles gambiae</em> metabolizes pyrethroids: sequential metabolism of deltamethrin revealed (Publications)
Resistance to pyrethroid insecticides in the malaria vector Anopheles gambiae is a major threat to malaria control programmes. Cytochome P450-mediated detoxification is an important resistance mechani