Epidemiology of <em>Opisthorchis viverrini</em> in a rural district of southern Lao PDR (Publications)
In Lao PDR, detailed investigations on Opisthorchis viverrini are scarce. The objective was to document epidemiological features of O. viverrini infections in a highly endemic district. A random sampl
<em>Opisthorchis viverrini</em>: efficacy and tegumental alterations following administration of tribendimidine in vivo and in vitro (Publications)
The tegumental changes in adult Opisthorchis viverrini induced by tribendimidine were analyzed by scanning electron microscopy (SEM). We exposed O. viverrini to tribendimidine at a concentration of 10
Efficacy of praziquantel against <em>Schistosoma mekongi </em>and <em>Opisthorchis viverrini</em>: a randomized, single-blinded dose-comparison trial (Publications)
BACKGROUND: Schistosomiasis and opisthorchiasis are of public health importance in Southeast Asia. Praziquantel (PZQ) is the drug of choice for morbidity control but few dose comparisons have been mad
Severe morbidity due to <em>Opisthorchis viverrini</em> and <em>Schistosoma mekongi</em> infection in Lao PDR (Publications)
We assessed morbidity due to Opisthorchis viverrini and Schistosoma mekongi infections in 243 individuals in Lao PDR. Morbidity was associated with O. viverrini infection intensity. Co-infection with
Subtle to severe hepatobiliary morbidity in <em>Opisthorchis viverrini </em>endemic settings in Southern Laos (Publications)
Evidence of severe hepatobiliary morbidity associated with Opisthorchis viverrini liver fluke infection including cholangiocarcinoma (CCA) is scarce in Laos although O. viverrini infection is highly p
<em>CHI3L1 </em>polymorphisms, cord blood YKL-40 levels and later asthma development (Publications)
BACKGROUND: Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe forms of asthma. It has never
The genetic architecture of type 2 diabetes (Publications)
The genetic architecture of common traits, including the number, frequency, and effect sizes of inherited variants that contribute to individual risk, has been long debated. Genome-wide association st