Dose-response relationships and tegumental surface alterations in <em>Opisthorchis viverrini</em> following treatment with mefloquine in vivo and in... (Publications)
The treatment and control of opisthorchiasis relies on a single drug, praziquantel; hence, there is a need to develop novel opisthorchicidal drugs. We investigated the in vitro and in vivo activity of
Spatial distribution of, and risk factors for, <em>Opisthorchis viverrini</em> infection in southern Lao PDR (Publications)
BACKGROUND: Opisthorchis viverrini is a food-borne trematode species that might give rise to biliary diseases and the fatal cholangiocarcinoma. In Lao PDR, an estimated 2.5 million individuals are inf
Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with <em>Opisthorchis... (Publications)
BACKGROUND: Praziquantel is the only drug available for treatment of Opisthorchis viverrini, although in-vivo studies point to activity of mefloquine, artesunate, and tribendimidine against this liver
PCR diagnosis of <em>Opisthorchis viverrini</em> and <em>Haplorchis taichui</em> infections in a Lao community in an area of endemicity and comparison... (Publications)
Opisthorchiasis is a major public health problem in Southeast Asia. Affected individuals often have mixed infections with the liver fluke Opisthorchis viverrini and minute intestinal flukes such as Ha