Single nucleotide polymorphisms on the road to strain differentiation in <em>Mycobacterium ulcerans</em> (Publications)
The genomic fine-typing of strains of Mycobacterium ulcerans, the causative agent of the emerging human disease Buruli ulcer, is difficult due to the clonal population structure of geographical lineag
Optimized method for preparation of DNA from pathogenic and environmental mycobacteria (Publications)
Genomic studies on pathogenic and environmental mycobacteria are of growing interest for understanding of their evolution, distribution, adaptation, and host-pathogen interaction. Since most mycobacte
Optimized DNA preparation from mycobacteria (Publications)
Extraction of genomic DNA from mycobacteria requires special consideration because (i) many mycobacterial species exhibit extremely slow growth, and thus produce only small amounts of starting materia
Membrane protein turnover by the m-AAA protease in mitochondria depends on the transmembrane domains of its subunits (Publications)
AAA proteases are membrane-bound ATP-dependent proteases that are present in eubacteria, mitochondria and chloroplasts and that can degrade membrane proteins. Recent evidence suggests dislocation of m
Protein degradation in mitochondria (Publications)
The biogenesis of mitochondria and the maintenance of mitochondrial functions depends on an autonomous proteolytic system in the organelle which is highly conserved throughout evolution. Components of
