Evaluation of human liver microtissues for drug screening on <em>Schistosoma mansoni </em>schistosomula (Publications)
Schistosomiasis is a major neglected tropical disease with more than 200 million infections annually. Despite only one drug, praziquantel, being available, the drug pipeline against schistosomiasis is
Changes in self-reported physical activity predict health-related quality of life among South African schoolchildren: Findings from the DASH... (Publications)
Introduction: Regular physical activity is associated with multiple health benefits for children. Evidence from cross-sectional studies suggests that physical activity is positively associated with he
Multisectoral approach to support use of insecticide-treated net for malaria prevention among mobile and migrant populations in Myanmar: a systematic... (Publications)
BACKGROUND: Myanmar is a premalaria elimination country with artemisinin-resistant malaria. A strategy for transmission control is focused on vulnerable groups such as mobile and migrant populations (
Study protocol of a cluster randomized controlled trial of strategies to increase antenatal iron and folic acid supplementation and malaria... (Publications)
BACKGROUND: Coverage of antenatal iron and folic acid supplementation (IFAS) and intermittent preventive treatment of malaria in pregnancy (IPTp) remains low in many countries. Evidence on the most ef
Sleeping hearts: 12 years after a follow up study on cardiac findings due to sleeping sickness (Publications)
Both American Trypanosomiasis (Chagas disease) and Human African Trypanosomiasis (HAT) are diseases caused by single-celled flagellate protozoan parasites. While cardiac complications such as conducti
Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and... (Publications)
BACKGROUND: Globally, the majority of people living with HIV have no or only limited access to HIV drug resistance testing to guide the selection of antiretroviral drugs. This is of particular concern
Performance of the Kato-Katz method and real time polymerase chain reaction for the diagnosis of soil-transmitted helminthiasis in the framework of a... (Publications)
BACKGROUND: Accurate, scalable and sensitive diagnostic tools are crucial in determining prevalence of soil-transmitted helminths (STH), assessing infection intensities and monitoring treatment effica
The discovery of novel antitrypanosomal 4-phenyl-6-(pyridin-3-yl)pyrimidines (Publications)
Human African trypanosomiasis, or sleeping sickness, is a neglected tropical disease caused by Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense which seriously affects human health in A