RAIN: machine learning-based identification for HIV-1 bNAbs (Publications)
Broadly neutralizing antibodies (bNAbs) are promising candidates for the treatment and prevention of HIV-1 infections. Despite their critical importance, automatic detection of HIV-1 bNAbs from immune
Human placental schistosomiasis-a systematic review of the literature (Publications)
BACKGROUND: Schistosome egg deposition in pregnant women may affect the placenta of infected mothers and cause placental schistosomiasis (PS). Histopathological examination of placental tissue is an i
Chemoproteomics validates selective targeting of <em>Plasmodium</em> M1 alanyl aminopeptidase as an antimalarial strategy (Publications)
New antimalarial drug candidates that act via novel mechanisms are urgently needed to combat malaria drug resistance. Here, we describe the multi-omic chemical validation of Plasmodium M1 alanyl metal
The number of comorbidities as an important cofactor to ASA class in predicting postoperative outcome: an international multicentre cohort study (Publications)
BACKGROUND: Multimorbidity is a growing burden in our ageing society and is associated with perioperative morbidity and mortality. Despite several modifications to the ASA physical status classificati
Venturicidin A affects the mitochondrial membrane potential and induces kDNA loss in <em>Trypanosoma brucei</em> (Publications)
Neglected tropical diseases caused by trypanosomatid parasites have devastating health and economic consequences, especially in tropical areas. New drugs or new combination therapies to fight these pa
Availability of published evidence on coverage, cost components, and funding support for digitalisation of infectious disease surveillance in Africa,... (Publications)
BACKGROUND: The implementation of digital disease surveillance systems at national levels in Africa have been challenged by many factors. These include user applicability, utility of IT features but a
Population assessment of health system performance in 16 countries (Publications)
OBJECTIVE: To demonstrate how the new internationally comparable instrument, the People's Voice Survey, can be used to contribute the perspective of the population in assessing health system performan
Efficacy thresholds and target populations for antiviral COVID-19 treatments to save lives and costs: a modelling study (Publications)
Background: In 2023 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared endemic, yet hospital admissions have persisted and risen within populations at high and moderate risk of
Rapid appraisal of liver diseases using transient elastography, abdominal ultrasound, and microbiology in Côte d'Ivoire: a single-center study (Publications)
BACKGROUND: Liver diseases of infectious and non-infectious etiology cause considerable morbidity and mortality, particularly in low- and middle-income countries (LMICs). However, data on the prevalen