Efficacy and safety of ascending doses of moxidectin against<em> Strongyloides stercoralis</em> infections in adults: a randomised, parallel-group,... (Publications)
BACKGROUND: Strongyloidiasis represents a major public health issue, particularly in resource-limited countries. Preliminary studies suggest that moxidectin might serve as an alternative to the only a
Evaluation of a duplex real-time PCR in human serum for simultaneous detection and differentiation of <em>Schistosoma mansoni</em> and <em>Schistosoma... (Publications)
BACKGROUND: We evaluated a one-tube multiplex real-time PCR targeting DNA of Schistosoma haematobium complex and S. mansoni complex in serum samples obtained at different German diagnostic centers. ME
Neue Parameter für die Wirkstofftestung gegen <em>Trypanosoma cruzi</em> (Publications)
Chagas disease is a zoonosis caused by Trypanosoma cruzi and transmitted by triatomine bugs. Autochthonous to Latin America, Chagas disease has spread globally through travel and migration. New drugs
Targeted capture and sequencing of <em>Orientia tsutsugamushi</em> genomes from chiggers and humans (Publications)
Scrub typhus is a febrile disease caused by Orientia tsutsugamushi, transmitted by larval stage Trombiculid mites (chiggers), whose primary hosts are small mammals. The phylogenomics of O. tsutsugamus
NO2 and PM2.5 exposures and lung function in Swiss adults: estimated effects of short-term exposures and long-term exposures with and without... (Publications)
BACKGROUND: The impact of nitrogen dioxide (NO2) and particulate matter with an aerodynamic diameter of less than or equal to 2.5. microns (PM2.5) exposures on lung function has been investigated main
Role of human Pegivirus infections in whole <em>Plasmodium falciparum </em>sporozoite vaccination and controlled human malaria infection in African... (Publications)
BACKGROUND: Diverse vaccination outcomes and protection levels among different populations pose a serious challenge to the development of an effective malaria vaccine. Co-infections are among many fac
The alkaloid-enriched fraction of <em>Pachysandra terminalis</em> (Buxaceae) shows prominent activity against <em>Trypanosoma brucei rhodesiense</em> (Publications)
In the course of our studies on antiprotozoal natural products and following our recent discovery that certain aminosteroids and aminocycloartanoid compounds from Holarrhena africana A. DC. (Apocynace
Ambient air pollution exposure and chronic bronchitis in the Lifelines cohort (Publications)
BACKGROUND: Few large studies have assessed the relationship of long-term ambient air pollution exposure with the prevalence and incidence of symptoms of chronic bronchitis and cough. METHODS: We leve