Activation, structure, biosynthesis and bioactivity of glidobactin-like proteasome inhibitors from <em>Photorhabdus laumondii</em> (Publications)
The glidobactin-like natural products (GLNPs) glidobactin A and cepafungin I have been reported to be potent proteasome inhibitors and are regarded as promising candidates for anti-cancer drug develop
Unusual derivatives from <em>Hypericum scabrum</em> (Publications)
Three new compounds (1-3) with unusual skeletons were isolated from the n-hexane extract of the air-dried aerial parts of Hypericum scabrum. Compound 1 represents the first example of an esterified po
Impact of social accountability monitoring on health facility performance: evidence from Tanzania (Publications)
Social accountability programs are increasingly used to improve the performance of public service providers in low-income settings. Despite their growing popularity, evidence on the effectiveness of s
Enhancing the understanding of resilience in health systems of low- and middle-income countries: a qualitative evidence synthesis (Publications)
Background A country’s health system faces pressure when hit by an unexpected shock, such as what we observe in the midst of the coronavirus disease 2019 (COVID-19) pandemic. The concept of resilience
Structure of trypanosome coat protein VSGsur and function in suramin resistance (Publications)
Suramin has been a primary early-stage treatment for African trypanosomiasis for nearly 100 yr. Recent studies revealed that trypanosome strains that express the variant surface glycoprotein (VSG) VSG
Young people's experiences using an on-demand mobile health sexual and reproductive health text message intervention in Kenya: qualitative study (Publications)
BACKGROUND: Digital health usability assessments can help explain how well mobile health (mHealth) apps targeting young people with sexual and reproductive health (SRH) information performed and wheth
Effectiveness of school-based preventive chemotherapy strategies for sustaining the control of schistosomiasis in Côte d’Ivoire: results of a 5-year... (Publications)
BACKGROUND: Preventive chemotherapy using praziquantel is the mainstay for schistosomiasis control. However, there is little evidence on what is supposed to be the most effective school-based treatmen
Longitudinal monitoring of SARS-CoV-2 RNA on high-touch surfaces in a community setting (Publications)
Environmental surveillance of surface contamination is an unexplored tool for understanding transmission of SARS-CoV-2 in community settings. We conducted longitudinal swab sampling of high-touch non-
A comparative evaluation of mobile medical APPS (MMAS) for reading and interpreting malaria rapid diagnostic tests (Publications)
BACKGROUND: The World Health Organization recommends confirmatory diagnosis by microscopy or malaria rapid diagnostic test (RDT) in patients with suspected malaria. In recent years, mobile medical app
