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1. Durchgängiger Strategieprozess als Erfolgsfaktor einer exzellenten Organisation (Publications)

   Durchgängiger Strategieprozess als Erfolgsfaktor einer exzellenten Organisation

   Relevance:

   Das Generieren von neuem Wissen zu drängenden Fragen der öffentlichen Gesundheit, deren Umsetzung und Skalierung sind ressourcenintensive Tätigkeiten, die nicht alleine über kompetitive Forschungsgeld

2. The pharmacokinetics and drug-drug interactions of ivermectin in <em>Aedes aegypti</em> mosquitoes (Publications)

   The pharmacokinetics and drug-drug interactions of ivermectin in <em>Aedes aegypti</em> mosquitoes

   Relevance:

   Mosquitoes are vectors of major diseases such as dengue fever and malaria. Mass drug administration of endectocides to humans and livestock is a promising complementary approach to current insecticide

3. Antiprotozoal structure-activity relationships of synthetic leucinostatin derivatives and elucidation of their mode of action (Publications)

   Antiprotozoal structure-activity relationships of synthetic leucinostatin derivatives and elucidation of their mode of action

   Relevance:

   Leucinostatin A is one of the most potent antiprotozoal compounds ever described, but little was known on structure-activity relationships (SAR). We used Trypanosoma brucei as a protozoal model organi

4. A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: is it time to... (Publications)

   A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: is it time to reconsider the current contraindication?

   Relevance:

   BACKGROUND: Oral ivermectin is a safe broad spectrum anthelminthic used for treating several neglected tropical diseases (NTDs). Currently, ivermectin use is contraindicated in children weighing less

5. Variation in calculating and reporting antimalarial efficacy against<em> Plasmodium falciparum</em> in sub-Saharan Africa: a systematic review of... (Publications)

   Variation in calculating and reporting antimalarial efficacy against<em> Plasmodium falciparum</em> in sub-Saharan Africa: a systematic review of published reports

   Relevance:

   Antimalarials, in particular artemisinin-based combination therapies (ACTs), are critical tools in reducing the global burden of malaria, which is concentrated in sub-Saharan Africa. Performing and re

6. Variants associated with <em>HHIP</em> expression have sex-differential effects on lung function (Publications)

   Variants associated with <em>HHIP</em> expression have sex-differential effects on lung function

   Relevance:

   Background: Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the f

7. Exposure to multiple pesticides and neurobehavioral outcomes among smallholder farmers in Uganda (Publications)

   Exposure to multiple pesticides and neurobehavioral outcomes among smallholder farmers in Uganda

   Relevance:

   BACKGROUND: Multiple epidemiological studies have shown that exposure to single pesticide active ingredients or chemical groups is associated with adverse neurobehavioral outcomes in farmers. In agric

8. Is universal health coverage affordable? Estimated costs and fiscal space analysis for the Ethiopian essential health services package (Publications)

   Is universal health coverage affordable? Estimated costs and fiscal space analysis for the Ethiopian essential health services package

   Relevance:

   Estimating the required resources for implementing an essential health services package (EHSP) is vital to examine its feasibility and affordability. This study aimed to estimate the financial resourc

9. Case-control diagnostic accuracy study of a non-sputum CD38-based TAM-TB test from a single milliliter of blood (Publications)

   Case-control diagnostic accuracy study of a non-sputum CD38-based TAM-TB test from a single milliliter of blood

   Relevance:

   Background: CD4 T cell phenotyping-based blood assays have the potential to meet WHO target product profiles (TPP) of non-sputum-biomarker-based tests to diagnose tuberculosis (TB). Yet, substantial r

10. Health risk assessment for exposure to nitrate in drinking water in Central Java, Indonesia (Publications)

    Health risk assessment for exposure to nitrate in drinking water in Central Java, Indonesia

    Relevance:

    Since 2005, over 30 epidemiological studies have evaluated the association between nitrate in drinking water and adverse health outcomes. Conditions that lead to nitrate pollution in water, such as op