Structural basis of malaria RIFIN binding by LILRB1-containing antibodies (Publications)
Some Plasmodium falciparum repetitive interspersed families of polypeptides (RIFINs)—variant surface antigens that are expressed on infected erythrocytes1—bind to the inhibitory receptor LAIR1, and in
Validation of a human-serum-based <em>in vitro </em>growth method for drug screening on juvenile development stages of <em>Schistosoma mansoni</em> (Publications)
BACKGROUND: Schistosomiasis affects over 200 million people worldwide but only praziquantel is available for treatment and control. Drug discovery is often based on phenotypic drug screening, involvin
The long-term impact of the Leprosy Post-Exposure Prophylaxis (LPEP) program on leprosy incidence: a modelling study (Publications)
BACKGROUND: The Leprosy Post-Exposure Prophylaxis (LPEP) program explored the feasibility and impact of contact tracing and the provision of single dose rifampicin (SDR) to eligible contacts of newly
Estimating true prevalence of <em>Schistosoma mansoni</em> from population summary measures based on the Kato-Katz diagnostic technique (Publications)
BACKGROUND: The prevalence of Schistosoma mansoni infection is usually assessed by the Kato-Katz diagnostic technique. However, Kato-Katz thick smears have low sensitivity, especially for light infect
Comparing methods to impute missing daily ground-level PM10 concentrations between 2010-2017 in South Africa (Publications)
Good quality and completeness of ambient air quality monitoring data is central in supporting actions towards mitigating the impact of ambient air pollution. In South Africa, however, availability of
Trends in extrapulmonary TB cases at three teaching hospitals in Ghana, 2008-2017 (Publications)
SETTING: Three teaching hospitals in Ghana. OBJECTIVE: To elucidate trends in demographics, clinical characteristics and treatment outcomes in extrapulmonary TB (EPTB) patients. DESIGN: This was a ret
Sleeping sickness survey in the Serengeti [16mm film] (Publications)
"Die Serengeti und ihre Umgebung als Reservoir (besonders die Wildtiere) für Trypanosomen wird von der EATRO (East African Trypanosomiasis Research Organization) und dem Schweizerischen Tropeninstitut
Burden of soil-transmitted helminth infection in pregnant refugees and migrants on the Thailand-Myanmar border: results from a retrospective cohort (Publications)
BACKGROUND: Soil-transmitted helminth (STH) infections are widespread in tropical and subtropical regions. While many STH infections are asymptomatic, vulnerable populations (e.g., pregnant women) fac
The influence of roads on the fine-scale population genetic structure of the dengue vector <em>Aedes aegypti</em> (Linnaeus) (Publications)
Dengue is endemic in tropical and subtropical countries and is transmitted mainly by Aedes aegypti. Mosquito movement can be affected by human-made structures such as roads that can act as a barrier.
Health studies in the context of artisanal and small-scale mining: a scoping review (Publications)
Artisanal and small-scale mining (ASM) is an important livelihood activity in many lowand middle-income countries. It is widely acknowledged that there are a myriad of health risk and opportunities as
