New derivatives of the multi-stage active Malaria Box compound MMV030666 and their antiplasmodial potencies (Publications)
MMV’s Malaria Box compound MMV030666 shows multi-stage activity against various strains of Plasmodium falciparum and lacks resistance development. To evaluate the importance of its diarylether partial
"It's the poverty": stakeholder perspectives on barriers to secondary education in rural Burkina Faso (Publications)
Universal primary and secondary education is a key target of the Sustainable Development Goals. While substantial gains have been made at the primary school level, progress towards universal secondary
Evaluation of the diagnostic performance of PanbioTM Abbott SARS-CoV-2 rapid antigen test for the detection of COVID-19 from suspects attending ALERT... (Publications)
BACKGROUND: The emergence and rapid spread of coronavirus disease 2019 (COVID-19), a potentially lethal disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is causing publi
Efficacy and safety of acoziborole in patients with human African trypanosomiasis caused by <em>Trypanosoma brucei gambiense</em>: a multicentre,... (Publications)
Summary Background Human African trypanosomiasis caused by Trypanosoma brucei gambiense (gambiense HAT) in patients with late-stage disease requires hospital admission to receive nifurtimox–eflornithi
Introduction (Publications)
The geographical focus of this book pertains to Europe and Central Asia, while thematically, the seven chapters concentrate on a group of diseases, collec tively termed neglected tropical diseases (NT
Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations (Publications)
Genome-wide association studies rely on the statistical inference of untyped variants, called imputation, to increase the coverage of genotyping arrays. However, the results are often suboptimal in po
R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with <em>Schistosoma mansoni</em> and... (Publications)
Racemic praziquantel (PZQ) is the standard treatment for schistosomiasis and liver fluke infections (opisthorchiasis and clonorchiasis). The development of an optimal pediatric formulation and dose se
The relationship between harmful alcohol use and antiretroviral non-adherence in people accessing HIV treatment in Cape Town, South Africa: an... (Publications)
Harmful alcohol consumption can significantly compromise adherence to antiretroviral therapy (ART). Prior research has identified aggregate relationships between alcohol use and ART non-adherence, lar