Pharmacokinetic modelling and simulation to optimize albendazole dosing in hookworm- or <em>Trichuris trichiura</em>-infected infants to adults (Publications)
BACKGROUND: Albendazole is the most commonly used drug in preventive chemotherapy programmes against soil-transmitted helminth (STH) infections, with the standard dose of 400 mg resulting in suboptima
Equity in health insurance schemes enrollment in low and middle-income countries: a systematic review and meta-analysis (Publications)
BACKGROUND: Ensuring access to essential quality health services and reducing financial hardship for all individuals regardless of their ability to pay are the main goals of universal health coverage.
Effects of a partially supervised conditioning program in cystic fibrosis: an international multicenter, randomized controlled trial (ACTIVATE-CF) (Publications)
Rationale: The long-term effects of vigorous physical activity (PA) on lung function in cystic fibrosis are unclear. Objectives: To evaluate effects of a 12-month partially supervised PA intervention
Multi-insecticide resistant malaria vectors in the field remain susceptible to malathion, despite the presence of <em>Ace1</em> point mutations (Publications)
Insecticide resistance in Anopheles mosquitoes is seriously threatening the success of insecticide-based malaria vector control. Surveillance of insecticide resistance in mosquito populations and iden
Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in... (Publications)
Buruli ulcer (BU) is a neglected tropical disease caused by subcutaneous infection with Mycobacterium ulcerans and its exotoxin mycolactone. BU displays coagulative necrosis and widespread fibrin depo
<em>Plasmodium falciparum</em> parasite prevalence in East Africa: updating data for malaria stratification (Publications)
The High Burden High Impact (HBHI) strategy for malaria encourages countries to use multiple sources of available data to define the sub-national vulnerabilities to malaria risk, including parasite pr
Detection of asymptomatic malaria in Asian countries: a meta-analysis of diagnostic accuracy (Publications)
Background: Achieving malaria elimination requires the targeting of the human reservoir of infection, including those patients with asymptomatic infection. The objective was to synthesise evidence on