A modular approach to the antifungal sphingofungin family: concise total synthesis of sphingofungin A and C (Publications)
Sphingofungins are fungal natural products known to inhibit the biosynthesis of sphingolipids which play pivotal roles in various cell functions. Here, we report a short and flexible synthetic approac
Delayed cerebellar ataxia, a rare post-malaria neurological complication: case report and review of the literature (Publications)
Delayed cerebellar ataxia (DCA) is a rare post-malarial neurological complication with unknown pathomechanism characterized by its self-limiting course and favorable outcome. We report a case of DCA f
Alternative complement pathway inhibition does not abrogate meningococcal killing by serum of vaccinated individuals (Publications)
Dysregulation of complement activation causes a number of diseases, including paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. These conditions can be treated with monoclona
Residential greenness-related DNA methylation changes (Publications)
BACKGROUND: Residential greenness has been associated with health benefits, but its biological mechanism is largely unknown. Investigation of greenness-related DNA methylation profiles can contribute
Substantial reduction in particulate matter air pollution across Europe during 2006-2019: a spatiotemporal modeling analysis (Publications)
Air pollution poses the largest environmental health risk in Europe. Particulate matter (PM) concentrations are the most harmful pollutants representing the main air quality indicator in the Sustainab
Long-term outcome after SARS-CoV-2 infection in healthcare workers: a single centre cohort study (Publications)
BACKGROUND: Long-term symptoms after acute COVID-19 are highly debated. Nevertheless, data on long-term symptoms of COVID-19 in healthcare workers are scarce. METHODS: We assessed frequency and risk f
<em>“It is like we are living in a different world”</em>: health inequity in communities surrounding industrial mining sites in Burkina Faso,... (Publications)
Background: Health equity features prominently in the 2030 Agenda for Sustainable Development, yet there are wide disparities in health between and within countries. In settings of natural resource ex
Unexpected ring‑opening of 2,3‑dihydropyridines (Publications)
The reaction of 2,3-dihydropyridines with sulfonyl halides surprisingly yielded open chain dienes with sulfonylimine structure. The products were specific out of several possible isomers and, therefor
Modifications and hybrids of 1,2,3,4‑tetrahydropyridinium salts and their antiprotozoal potencies (Publications)
The antiprotozoal activity of 1-benzyltetrahydropyridin-4-yliden iminium salts is reported. This paper describes the preparation of a series of analogs from dihydropyridines or dihydrothiopyrans as ed