Prevalence, incidence and predictors of renal impairment in persons with HIV receiving protease-inhibitors in rural Tanzania (Publications)
OBJECTIVE: Ritonavir-boosted protease inhibitors (bPI) in people living with HIV (PLWH) have been associated with renal impairment. Limited data are available from rural sub-Saharan Africa. METHODS: U
Leishmaniasis in Europe and Central Asia: epidemiology, impact of habitat and lifestyle changes, HIV coinfection (Publications)
Visceral leishmaniasis (VL) and cutaneous leishmaniasis (CL) are endemic to the European region. Mainly the Mediterranean basin, southern Cauca sus, and Central Asia have a long history of outbreaks a
Diagnosis and treatment of neglected tropical diseases in Europe: laboratory infrastructure, diagnostic techniques, disease notification, and... (Publications)
An accurate laboratory diagnosis of neglected tropical diseases (NTDs) is crucial for targeted treatment, as the clinical symptomatology alone is frequently insufficient to distinguish between specifi
Soil-transmitted helminthiasis in Europe and Central Asia: an update on the epidemiology and control efforts (Publications)
Soil-transmitted helminth infections are among the most prevalent neglected tropical diseases. Infections are caused by a group of parasitic worms transmitted via soil contaminated with feces from inf
Investigational medicinal products, related costs and hospital pharmacy services for investigator-initiated trials: a mixed-methods study (Publications)
BACKGROUND: Conducting high quality investigator-initiated trials (IITs) is challenging and costly. The costs of investigational medicinal products (IMPs) in IITs and the role of hospital pharmacies i
<em>Mycobacterium leprae</em> infection in a wild nine-banded armadillo, Nuevo León, Mexico (Publications)
Nine-banded armadillos (Dasypus novemcinctus) are naturally infected with Mycobacterium leprae and are implicated in the zoonotic transmission of leprosy in the United States. In Mexico, the existence
Long-term exposure to ambient air pollution and asthma symptom score in the CONSTANCES cohort (Publications)
BACKGROUND: The asthma symptom score allows to consider asthma as a continuum and to investigate its risk factors. One previous study has investigated the association between asthma score and air poll
G-quadruplexes in helminth parasites (Publications)
Parasitic helminths infecting humans are highly prevalent infecting approximately 2 billion people worldwide, causing inflammatory responses, malnutrition and anemia that are the primary cause of morb
Our exciting journey to ACT-451840 (Publications)
We describe our work resulting in the selection of ACT-451840 ( 38 ) as a novel antimalarial drug with a novel mode of action. The compound was broadly characterized in vitro as well as in vivo in rat