From genetic epidemiology to exposome and systems epidemiology (Publications)
Genetic epidemiology investigates the contribution of germline gene variants to disease etiology. The genetic architecture of many diseases exhibiting Mendelian inheritance patterns was decoded throug
Kikuchi-Fujimoto disease triggered by systemic lupus erythematosus and <em>Mycoplasma pneumoniae</em> infection- a report of a case and a review of... (Publications)
Kikuchi-Fujimoto disease (KFD) is a necrotizing histiocytic lymphadenitis that was described for the first time in 1972 in Japan. Its etiology is still not fully understood. It has been reported in as
The spread of chloramphenicol-resistant <em>Neisseria meningitidis</em> in Southeast Asia (Publications)
OBJECTIVES: Invasive disease caused by Neisseria meningitidis is a significant health concern globally, but our knowledge of the prevailing serogroups, antimicrobial susceptibility patterns, and genet
A systems approach to assessing complexity in health interventions: an effectiveness decay model for integrated community case management (Publications)
Complexity is inherent to any system or program. This is especially true of integrated interventions, such as integrated community case management (iCCM). iCCM is a child health strategy designed to p
Immunoglobulin recognition of fecal bacteria in stunted and non-stunted children: findings from the Afribiota study (Publications)
BACKGROUND: Child undernutrition is a global health issue that is associated with poor sanitation and an altered intestinal microbiota. Immunoglobulin (Ig) A mediates host-microbial homeostasis in the
Associations of preconception exposure to air pollution and greenness with offspring asthma and hay fever (Publications)
We investigated if greenness and air pollution exposure in parents’ childhood affect offspring asthma and hay fever, and if effects were mediated through parental asthma, pregnancy greenness/pollution
HIV coinfection is associated with low fitness <em>rpoB</em> variants in rifampicin-resistant <em>Mycobacterium tuberculosis</em> (Publications)
We analysed 312 drug-resistant genomes of Mycobacterium tuberculosis (Mtb) collected from HIV coinfected and HIV negative TB patients from nine countries with a high tuberculosis burden. We found that
Non-invasive monitoring of drug action: a new live <em>in vitro</em> assay design for Chagas' disease drug discovery (Publications)
New assay designs are needed to improve the predictive value of the Trypanosoma cruzi in vitro tests used as part of the Chagas' disease drug development pipeline. Here, we employed a green fluorescen
Travel patterns, risk behaviour and health problems of travellers with rheumatic diseases compared to controls: a multi-centre, observational study (Publications)
BACKGROUND: Patients with chronic conditions travel around the world more than ever. Only few studies have examined travel patterns and health outcomes of patients with rheumatic diseases during inter
Incorporating operational research in programmes funded by the Global Fund to Fight AIDS, Tuberculosis and Malaria in four sub-Saharan African... (Publications)
BACKGROUND: The current study builds upon a previous situation analysis of the extent to which grants from the Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund) are being utilized to s
