The competitive cost of antibiotic resistance in <em>Mycobacterium tuberculosis</em> (Publications)
Mathematical models predict that the future of the multidrug-resistant tuberculosis epidemic will depend on the fitness cost of drug resistance. We show that in laboratory-derived mutants of Mycobacte
Global phylogeography of <em>Mycobacterium tuberculosis</em> and implications for tuberculosis product development (Publications)
New tools for controlling tuberculosis are urgently needed. Despite our emerging understanding of the biogeography of Mycobacterium tuberculosis, the implications for development of new diagnostics, d
Drug repurposing in the chemotherapy of infectious diseases (Publications)
Repurposing is a universal mechanism for innovation, from the evolution of feathers to the invention of Velcro tape. Repurposing is particularly attractive for drug development, given that it costs mo
Accessibility of malaria commodities in Geita District Council, mainland Tanzania: the experiences from healthcare providers and clients (Publications)
BACKGROUND: Access to essential malaria commodities is a cornerstone in malaria control. However optimal availability and access to essential malaria commodities remain a challenge in Tanzania. Theref
Same-day versus rapid ART initiation in HIV-positive individuals presenting with symptoms of tuberculosis: protocol for an open-label randomized... (Publications)
BACKGROUND: In absence of contraindications, same-day initiation (SDI) of antiretroviral therapy (ART) is recommended for people testing HIV-positive who are ready to start treatment. Until 2021, Worl