Investigating mosquito net durability for malaria control in Tanzania - attrition, bioefficacy, chemistry, degradation and insecticide resistance... (Publications)
(LLINs) are one of the major malaria vector control tools, with most countries adopting free or subsidised universal coverage campaigns of populations at-risk from malaria. It is essential to understand [...] data sets to provide GIS maps for use in health surveillance and decision making by the National Malaria Control Program (NMCP). DISCUSSION: The data will be of importance to policy makers and vector control [...] for the maintenance of high and cost-effective coverage and to maximise...
Transmission of malaria in relation to distribution and coverage of long-lasting insecticidal nets in central Côte d'Ivoire (Publications)
BACKGROUND: The use of long-lasting insecticidal nets (LLINs) is an effective malaria control strategy. However, there are challenges to achieve high coverage, such as distribution sustainability, and [...] study assessed the effect of LLINs coverage and contextual factors on entomological indicators of malaria in rural Côte d'Ivoire. METHODS: The study was carried out between July 2009 and May 2012 in three [...] of central Côte d'Ivoire. In Bozi and Yoho, LLINs were distributed free of charge...
Community response to intermittent preventive treatment of malaria in infants (IPTi) in Papua New Guinea (Publications)
Africa this article aims to investigate the acceptability of intermittent preventive treatment of malaria in infants (IPTi) in Papua New Guinea (PNG). METHODS: A questionnaire was administered to mothers [...] is little evidence that IPTi has negative impacts on attitudes to EPI, EPI adherence or existing malaria prevention practices. CONCLUSION: The degree of similarity between findings from the acceptability [...] health cultures, appears to be accepted easily and has little impact on...
Improving health worker adherence to malaria treatment guidelines in Papua New Guinea: feasibility and acceptability of a text message reminder... (Publications)
whether a text message reminder service designed to support health worker adherence to a revised malaria treatment protocol is feasible and acceptable in Papua New Guinea (PNG). The study took place in [...] resources. In conclusion, a text message reminder service to support health worker adherence to the new malaria treatment protocol is feasible and acceptable in PNG. A rigorous pragmatic, effectiveness trial would
Potential causes and consequences of behavioural resilience and resistance in malaria vector populations: a mathematical modelling analysis (Publications)
evade fatal exposure to insecticidal nets and sprays represents the primary obstacle to eliminating malaria. However, it remains unclear which behaviours are most important for buffering mosquito and parasite
Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young... (Publications)
BACKGROUND: A malaria vaccine could be an important addition to current control strategies. We report the safety and vaccine efficacy (VE) of the RTS,S/AS01 vaccine during 18 mo following vaccination at [...] at 11 African sites with varying malaria transmission. METHODS AND FINDINGS: 6,537 infants aged 6-12 wk and 8,923 children aged 5-17 mo were randomized to receive three doses of RTS,S/AS01 or comparator [...] comparator vaccine. VE against clinical malaria in children during the 18 mo after...
The exit interview as a proxy measure of malaria case management practice: sensitivity and specificity relative to direct observation (Publications)
sensitivity and specificity of exit interviews as a measure of malaria case management practice as compared to direct observation.MethodsThe malaria case management of 1654 febrile patients attending 110 health [...] specificity from 70.6% to 98.1%.ConclusionThe exit interview appears to be a valid measure of objective malaria case management practices such as the completion of a diagnostic test or the provision of antimalarial [...] but may be a less valid measure of low frequency, subjective...
Managing the sick child in the era of declining malaria transmission: development of ALMANACH, an electronic algorithm for appropriate use of... (Publications)
based on a respiratory rate threshold of 50 assessed twice for febrile children 12-59 months; iv) malaria rapid diagnostic test performed for all febrile children. In the absence of identified source of
Age-shifting in malaria incidence as a result of induced immunological deficit: a simulation study (Publications)
Effective population-level interventions against Plasmodium falciparum malaria lead to age-shifts, delayed morbidity or rebounds in morbidity and mortality whenever they are deployed in ways that do not [...] shifting of incidence induced by either pre-erythrocytic vaccination (PEV) programmes or seasonal malaria chemo-prevention (SMC), using an ensemble of individual-based stochastic simulation models of P. [...] life-cycle and on human demography. Effects of transmission intensity, and of...
Applications and limitations of Centers for Disease Control and Prevention miniature light traps for measuring biting densities of African malaria... (Publications)
BACKGROUND: Measurement of densities of host-seeking malaria vectors is important for estimating levels of disease transmission, for appropriately allocating interventions, and for quantifying their impact [...] methods for their consistency in sampling indoor-feeding mosquitoes belonging to the two major taxa of malaria vectors across Africa, the Anopheles gambiae sensu lato complex and the Anopheles funestus s.l. group [...] easy to deploy on a large scale. Spatial and temporal variation in...