Malaria standby emergency treatment (SBET) for travelers visiting malaria endemic areas: a systematic review and meta-analysis (Publications)
Malaria prevention methods for travelers to low or moderate malaria risk areas varies and remains controversial. Standby Emergency Treatment (SBET) for malaria is one possible strategy increasingly recommended [...] proportion carrying SBET, the response to fever (use of SBET, health facility attendance, use of malaria rapid diagnostic test [mRDT]), adverse events to SBET, and the proportion using SBET incorrectly [...] current SBET strategy should be considered, such as better selection of...
Rapid diagnostic test-based management of malaria: an effectiveness study in Papua New Guinean infants with <em>Plasmodium falciparum</em> and... (Publications)
Background. In malaria-endemic areas it is recommended that febrile children be tested for malaria by rapid diagnostic test (RDT) or blood slide (BS) and receive effective malaria treatment only if results [...] P. vivax malaria on the basis of RDT but BSs were negative; 16 had LRTIs; 3 had alternative diagnoses. Of these 24, 22 were cured at day 28. Two children died of illnesses other than malaria and were RDT [...] RDT and BS negative at the initial and subsequent visits.Conclusion. Treatment...
Epidemiological characterization of malaria in rural southern Tanzania following China-Tanzania pilot joint malaria control baseline survey (Publications)
BACKGROUND: Malaria is an important public health problem in Tanzania. The latest national malaria data suggests rebound of the disease in the country. Anopheles arabiensis, a mosquito species renowned [...] conducted to determine malaria parasite prevalence and associated risk exposures prior to piloting the T3-initiative of World Health Organization integrated with Chinese malaria control experience aimed [...] additional reduction of malaria in the area. METHODS: The study was conducted from...
Assessment of ultra-sensitive malaria diagnosis versus standard molecular diagnostics for malaria elimination: an in-depth molecular community... (Publications)
BACKGROUND: Submicroscopic malaria infections contribute to transmission in exposed populations but their extent is underestimated even by standard molecular diagnostics. Sophisticated sampling and ul [...] sensitive methods with the aim to understand what diagnostic sensitivity is necessary to guide malaria interventions. METHODS: Venous blood samples were collected from participants in a cross-sectional
Effectiveness of intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy on placental malaria, maternal anaemia and... (Publications)
areas with different malaria transmission intensities. METHODS: Prospective observational study recruiting pregnant women in two health facilities in areas with high and low malaria transmission intensities [...] risk factors for placental malaria (OR 2.4; CI 1.1-5.0; P = 0.025) and (OR 9.4; CI 3.2-27.7; P < 0.001), respectively. IPTp was associated with a lower risk of placental malaria (OR 0.3; CI 0.1-1.0; P = [...] the low transmission area to prevent one case of placental malaria....
"My children and I will no longer suffer from malaria": a qualitative study of the acceptance and rejection of indoor residual spraying to prevent... (Publications)
BACKGROUND: The objective of this study was to identify attitudes and misconceptions related to acceptance or refusal of indoor residual spraying (IRS) in Tanzania for both the general population and
Reductions in malaria and anaemia case and death burden at hospitals following scale-up of malaria control in Zanzibar, 1999-2008 (Publications)
CONCLUSIONS: Scaling-up effective malaria interventions reduced malaria-related burden at health facilities by over 75% within 5 years. In high-malaria settings, intensified malaria control can substantially [...] groups combined, malaria deaths had fallen by an estimated 90% (95% confidence interval 55-98%)(p < 0.025), malaria in-patient cases by 78% (48-90%), and parasitologically-confirmed malaria out-patient cases [...] BACKGROUND: In Zanzibar, the Ministry of Health and partners...