Humoral immune responses during a malaria vaccine trial in Tanzanian infants (Publications)
The development of a malaria vaccine is a priority for improved and sustained malaria control. Optimal use of a vaccine in Africa will only be achieved if it can be delivered through the Expanded Programme [...] preimmunization levels by 2 years of age and which was not associated with protection against clinical malaria. The vaccine induced no IgG antibodies against (NANP)50 or P. falciparum lysates. SPf66 stimulated
Comparative cost models of a liquid nitrogen vapor phase (LNVP) cold chain-distributed cryopreserved malaria vaccine vs. a conventional vaccine (Publications)
the costs and compare these costs to those that would be incurred in distributing a 'conventional' malaria vaccine through the EPI. Capital and recurrent costs for storage, transportation, labor, energy usage
Randomized double-blind controlled Phase I/IIa trial to assess the efficacy of malaria vaccine PfCS102 to protect against challenge with <em>P.... (Publications)
this Phase I/IIa double-blind controlled trial was to test the efficacy of the sporozoite-based malaria vaccine PfCS 282-383 (PfCS102) to protect against Plasmodium falciparum parasitaemia. 16 volunteers [...] antibodies against PfCS102 versus none control. 8/8 vaccinees and 6/6 controls challenged developed malaria parasitaemia. The duration from infection to onset of patent parasitaemia was similar in both groups
Safety and immunogenicity of a three-component blood-stage malaria vaccine in adults living in an endemic area of Papua New Guinea (Publications)
A Phase I safety and immunogenicity study with a three-component blood- stage malaria vaccine was conducted in adult male subjects living in an endemic area of Papua New Guinea. The preparations were
Habitat-based larval interventions: a new perspective for malaria control (Publications)
environmental management of mosquito larval habitats has been rekindled due to deterioration of malaria in tropical Africa. Environmental management programs were typically implemented as "all-out" campaigns [...] tiveness, and sustainability of such approaches, particularly when implemented along with other malaria control measures