Effects of seasonality and irrigation on malaria transmission in two villages in Côte d'Ivoire (Publications)
The seasonality of malaria transmission was investigated in two villages in central Cote d'Ivoire: one usually with irrigated rice farming (Zatta) and one without (Tiemelekro). Adult mosquitoes were collected
Estimated global resources needed to attain international malaria control goals (Publications)
international community with an estimate of the amount of financial resources needed to scale up malaria control to reach international goals, including allocations by country, year and intervention as [...] supporting services and programme strengthening activities in each of the 81 most heavily affected malaria-endemic countries. Two scenarios were evaluated, using different assumptions about the effect of [...] interventions on the needs for diagnosis and treatment. Current health...
Biologically meaningful coverage indicators for eliminating malaria transmission (Publications)
coverage beyond houses and humans, are required to eliminate malaria transmission in most settings. The overwhelming diversity of the world's malaria transmission systems and optimal strategies for controlling [...] insecticidal nets and indoor residual sprays, by feeding outdoors or upon animals, are primary malaria vectors in many tropical countries. They can also dominate residual transmission where high coverage
Human antibodies to recombinant protein constructs of <em>Plasmodium falciparum</em> Apical Membrane Antigen 1 (AMA1) and their associations with... (Publications)
ectodomain (both FVO and 3D7 allele constructs) prior to a malaria transmission season were significantly associated with protection from malaria in the following 6 months, even after adjusting for age and
Malaria-infected mice are cured by oral administration of new artemisinin derivatives (Publications)
a new series of 23 trioxane dimers has been prepared. Eleven of these new trioxane dimers cure malaria-infected mice via oral dosing at 3 x 30 mg/kg. The clinically used trioxane drug sodium artesunate [...] on day 6-7 postinfection. At only 3 x 10 mg/kg oral dosing, seven dimers prolong the lifetime of malaria-infected mice to days 14-17, more than double the chemotherapeutic effect of sodium artesunate. Ten