Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on... (Publications)
sub-micromolar range against Trypanosoma brucei rhodesiense and Trypanosoma cruzi, as well as the malaria parasite Plasmodium falciparum, which lack trypanothione metabolism. The inhibitors exhibit strong
Field evaluation of spatial repellency of metofluthrin-impregnated plastic strips against <em>Anopheles gambiae</em> complex in Bagamoyo, coastal... (Publications)
study reports the efficacy of the new prototypes of metofluthrin-impregnated plastic strips against malaria vectors, Anopheles gambiae complex, in the Kongo villages of Bagamoyo district in coastal Tanzania
Rapid mapping of schistosomiasis and other neglected tropical diseases in the context of integrated control programmes in Africa (Publications)
lessons from the mapping of human helminth infections may also be relevant for the rapid mapping of malaria as its control efforts are intensified
Synthesis, solution structure and immune recognition of an epidermal growth factor-like domain from <em>Plasmodium falciparum</em> merozoite surface... (Publications)
iented approach to the study and optimization of the antigenicity of the protein as a potential malaria vaccine candidate, whilst exploiting the immunopotentiating properties of influenza virosomes as
Monica Golumbeanu (People)
https://www.swisstph.ch/en/staff/profile/people/monica-golumbeanu
her research focuses on developing data-driven computational analyses and mathematical models of malaria infection dynamics to assess the impact of interventions on host and parasite populations. Previously
Alterations in local chromatin environment are involved in silencing and activation of subtelomeric var genes in <em>Plasmodium falciparum</em> (Publications)
family, undergoes antigenic variation and plays an important role in chronic infection and severe malaria. Only a single var gene is transcribed per parasite, and epigenetic control mechanisms are fundamental
Synthesis, solution structure and immune recognition of an epidermal growth factor-like domain from <em>Plasmodium falciparum</em> merozoite surface... (Publications)
iented approach to the study and optimization of the antigenicity of the protein as a potential malaria vaccine candidate, whilst exploiting the immunopotentiating properties of influenza virosomes as
Living on the edge: a longitudinal study of <em>Anopheles funestus</em> in an isolated area of Mozambique (Publications)
BACKGROUND: Understanding the survival strategies of malaria vectors at the edges of their distribution, where they are under stress from environmental conditions, may lead to the development of novel
Antigenic cross-reactivity between different alleles of the <em>Plasmodium falciparum </em>merozoite surface protein 2 (Publications)
encoding Plasmodium falciparum merozoite surface protein 2 (MSP2) was PCR amplified from blood of malaria patients, genotyped, and 19 distinct fragments were cloned and expressed in E. coli. The reactivity
Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on... (Publications)
sub-micromolar range against Trypanosoma brucei rhodesiense and Trypanosoma cruzi, as well as the malaria parasite Plasmodium falciparum, which lack trypanothione metabolism. The inhibitors exhibit strong