Cytochrome P450/ABC transporter inhibition simultaneously enhances ivermectin pharmacokinetics in the mammal host and pharmacodynamics in... (Publications)
drugs that kill blood-feeding arthropods, has been proposed as a complementary strategy to reduce malaria transmission. Ivermectin is one of the leading candidates given its excellent safety profile. Here
From innovation to application: social-ecological context, diagnostics, drugs and integrated control of schistosomiasis (Publications)
Compared to malaria, tuberculosis and HIV/AIDS, schistosomiasis remains a truly neglected tropical disease. Schistosomiasis, perhaps more than any other disease, is entrenched in prevailing social-ecological
Diagnosis of <em>Plasmodium falciparum</em> infection using ParaSight(R)-F test in blood and urine of Papua New Guinean children (Publications)
Rapid, simple, accurate and cheap methods are required for the diagnosis of malaria in endemic areas. The ParaSight(R)-F test, which is based on qualitative detection by monoclonal antibody of the Plasmodium
CRISPR-Cas9-modified <em>pfmdr1</em> protects <em>Plasmodium falciparum </em>asexual blood stages and gametocytes against a class of... (Publications)
Emerging resistance to first-line antimalarial combination therapies threatens malaria treatment and the global elimination campaign. Improved therapeutic strategies are required to protect existing drugs
Monitoring of selected health indicators in children living in a copper mine development area in northwestern Zambia (Publications)
The epidemiology of malaria, anaemia and malnutrition in children is potentially altered in mining development areas. In a copper extraction project in northwestern Zambia, a health impact assessment (HIA)
Sequence analysis of the MSP 1 gene of <em>Plasmodium falciparum</em> isolates from Hainan, China (Publications)
. METHODS: Genomic DNA was prepared directly from blood samples spotted on filter papers from 2 malaria patients from Baoting County, Hainan Province. PCR amplification of the target gene was carried out
The cost-effectiveness of permethrin impregnated bednets in preventing child mortality in Kassena-Nankana district of Northern Ghana (Publications)
bednets are now being widely promoted as an effective means of protecting African children against malaria, but there is little evidence of their cost-effectiveness. The impact on child mortality of introducing
Phase III study to compare intravenous with oral iron to treat iron deficiency anaemia (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/phase-iii-study-to-compare-intravenous-with-oral-iron-to-treat-iron-deficiency-anaemia
supply, different perception of medication needs and compliance as well as concomitant diseases like malaria, soil-transmitted helminths, schistosomiasis or HIV. All these factors may influence the efficacy
A path to cooperation between China and Mongolia towards the control of echinococcosis under the Belt and Road Initiative (Publications)
development goals, especially goal 3, target 3.3: by 2030, end the epidemics of AIDS, tuberculosis, malaria and neglected tropical diseases and combat hepatitis, water-borne diseases and other communicable
Chemoproteomics validates selective targeting of <em>Plasmodium</em> M1 alanyl aminopeptidase as an antimalarial strategy (Publications)
New antimalarial drug candidates that act via novel mechanisms are urgently needed to combat malaria drug resistance. Here, we describe the multi-omic chemical validation of Plasmodium M1 alanyl metal
