Dihydroartemisinin-piperaquine effectiveness for seasonal malaria chemoprevention in settings with extended seasonal malaria transmission in Tanzania (Publications)
course of DP for three consecutive months regardless of malaria infection status, and those in the control clusters received no intervention. Malaria infection was assessed at before the first-round and at [...] Effectiveness of dihydroartemisinin-piperaquine (DP) as seasonal malaria chemoprevention (SMC) was assessed in Nanyumbu and Masasi Districts. Between March and June 2021, children aged 3-59 months were [...] at 7 weeks after the third-round of DP in both arms. Malaria prevalence after...
Early whole blood transcriptional responses to radiation-attenuated <em>Plasmodium falciparum</em> sporozoite vaccination in malaria naive and malaria... (Publications)
radiation-attenuated P. falciparum sporozoites were analysed and compared across malaria-naive adult participants (IMRAS) and malaria-experienced adult participants (BSPZV1). Parasite dose and method of delivery [...] despite stark differences between the two studies, including route of vaccination and status of malaria exposure, responses were identified that were associated with protection after PfRAS vaccination
Attitudes, practices, and determinants of community care-seeking behaviours for fever/malaria episodes in the context of the implementation of... (Publications)
FGDs showed that participants had good knowledge about malaria symptoms, prevention tools, and effective treatment. Behaviour change regarding malaria treatment and free medication for children under five [...] CONCLUSIONS: The study showed appropriate knowledge about malaria and positive community care-seeking behaviour at health centres for fever/malaria episodes. This could potentially facilitate the implementation [...] BACKGROUND: Malaria case management relies on World Health Organization...
Reflections on the 2021 World Malaria Report and the future of malaria control (Publications)
The World Malaria Report, released in December 2021, reflects the unique challenges currently facing the global malaria community. The report showed the devastating toll of malaria, with an estimated 627 [...] the capacity of the continent to address the malaria challenge. African countries also face a convergence of biological threats that could redefine malaria control, notably widespread pyrethroid resistance [...] presents key insights from the 2021 World Malaria Report and reflections on...
Disparities of <em>Plasmodium falciparum</em> infection, malaria-related morbidity and access to malaria prevention and treatment among school-aged... (Publications)
There is limited knowledge on the malaria burden of school-aged children in Cote d'Ivoire. The aim of this study was to assess Plasmodium falciparum infection, malaria-related morbidity, use of preventive [...] preventive measures and treatment against malaria, and physical access to health structures among school-aged children across Cote d'Ivoire. METHODS: A national, cross-sectional study was designed, consisting [...] were interviewed to determine household socioeconomic status,...
Relationship between child survival and malaria transmission: an analysis of the malaria transmission intensity and mortality burden across Africa... (Publications)
relationship between malaria mortality and levels of transmission is unclear. Due to methodological limitations, earlier efforts to assess the linkage have lead to inconclusive results. The malaria transmission [...] assessing the malaria transmission-mortality relation involves more than the knowledge on the performance of interventions and control measures. This relation depends on the levels of malaria endemicity and [...] age and insecticide-treated nets (ITNs), were fitted to assess the...