Malaria elimination in Zanzibar: where next? (Publications)
progress made towards malaria elimination, effectiveness of the health systems in delivering malaria case management; and malaria financing. A desk review examined available malaria data, annual work plans [...] 2018, Zanzibar developed a national malaria strategic plan IV (2018-2023) to guide elimination of malaria by 2023. We assessed progress in the implementation of malaria activities as part of the end-term [...] with marked heterogeneity between areas. However, about 68% of the detected ma...
Species composition, infection rate and detection of resistant alleles in <em>Anopheles funestus</em> (Diptera: Culicidae) from Lare, a malaria... (Publications)
BACKGROUND: Anopheles funestus, which is considered as secondary vector of malaria in Ethiopia, is known to have several morphologically indistinguishable (sibling) species. Accurate identification of [...] wild type. None of the samples (N = 169) were found positive for Plasmodium (P. falciparum/ovale/malariae/vivax) detection. CONCLUSION: All An. funestus s.l. samples from Lare were molecularly identified
Spatial prediction of malaria prevalence in Papua New Guinea: a comparison of Bayesian decision network and multivariate regression modelling... (Publications)
performance when developing malaria prevalence maps due to the multiple interacting factors that drive malaria prevalence in different geographical areas. When developing malaria prevalence maps, BDNs may [...] BACKGROUND: Considerable progress towards controlling malaria has been made in Papua New Guinea through the national malaria control programme's free distribution of long-lasting insecticidal nets, improved [...] linear model, GLM) in terms of malaria spatial risk prediction accuracy....
Mapping the endemicity and seasonality of clinical malaria for intervention targeting in Haiti using routine case data (Publications)
Towards the goal of malaria elimination on Hispaniola, the National Malaria Control Program of Haiti and its international partner organisations are conducting a campaign of interventions targeted to high-risk
A brief history of selected malaria vaccine and medical interventions pursued by the Swiss Tropical and Public Health Institute and partners,... (Publications)
research portfolio as key elements for researching and applying evidence in malaria control and elimination as part of national malaria control programmes. [...] perspective. Its aim is to highlight the above-mentioned transformation by focusing on selected malaria research-cum-action interventions during the crucial period of the 1990s, which were tailored to
Knowledge of antimalarials and health seeking behaviour of households in case of suspected malaria in Democratic Republic of the Congo (Publications)
of the Congo (DRC) is heavily affected by malaria despite availability of effective treatments. Ignorance and unrecommended behaviour toward a suspected malaria case in households may contribute to this [...] urban Health Centres in each of the 11 previous provinces of DRC, all households with a case of malaria in the 15 days prior to the survey were selected. The patient or caregiver (responder) were interviewed [...] predictors of knowledge of recommended antimalarials and adequate behaviour...
Safety, immunogenicity and efficacy of PfSPZ vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase... (Publications)
infection in malaria-naive adults. Preclinical studies show that T cell-mediated immunity is required for protection and is readily induced in humans after vaccination. However, previous malaria exposure can [...] and vaccine efficacy (VE) in adults. We hypothesized that infants with less previous exposure to malaria would have improved immunity and protection. We conducted a multi-arm, randomized, double-blind, [...] tolerability, immunogenicity and efficacy of the PfSPZ Vaccine in infants in a...
Transfluthrin eave-positioned targeted insecticide (EPTI) reduces human landing rate (HLR) of pyrethroid resistant and susceptible malaria vectors in... (Publications)
of transfluthrin eave-positioned targeted insecticide (EPTI) depends on the resistance status of malaria vectors. METHODS: Ribbons treated with 5.25 g transfluthrin or untreated controls were used around
Analysis of contamination in cluster randomized trials of malaria interventions (Publications)
BACKGROUND: In cluster randomized trials (CRTs) of interventions against malaria, mosquito movement between households ultimately leads to contamination between intervention and control arms, unless they [...] which contamination measurably biases the estimate of effectiveness. A sigmoid function is fitted to malaria prevalence or incidence data as a function of the distance of households to the intervention boundary
