On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity (Publications)
To combat the global burden of malaria, development of new drugs to replace or complement current therapies is urgently required. Here, we show that the compound MMV1557817 is a selective, nanomolar i
Psychophysiological effects of walking in forests and urban built environments with disparate road traffic noise exposure: study protocol of a... (Publications)
BACKGROUND: Stress is a widespread phenomenon and reality of everyday life, entailing negative consequences for physical and psychological wellbeing. Previous studies have indicated that exposure to g
Identification of a family of species-selective complex I inhibitors as potential anthelmintics (Publications)
Soil-transmitted helminths (STHs) are major pathogens infecting over a billion people. There are few classes of anthelmintics and there is an urgent need for new drugs. Many STHs use an unusual form o
Health workers' perspectives on school-based mass drug administration control programs for soil-transmitted helminthiasis and schistosomiasis in Ogun... (Publications)
BACKGROUND: Soil-transmitted helminthiasis (STH) and schistosomiasis (SCH) are among the most prevalent neglected tropical diseases (NTDs), affecting 1.5 billion globally, with a significant burden in
Exploring evidence use and capacity for health services management and planning in Swiss health administrations: a mixed-method interview study (Publications)
BACKGROUND: Health administrations require evidence, meaning robust information, data, and research, on health services and systems. Little is known about the resources and processes available within
Diagnostic accuracy of a sequence-specific <em>Mtb</em>-DNA hybridization assay in urine: a case-control study including subclinical TB cases (Publications)
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) remains one of the deadliest infectious diseases globally. Timely diagnosis is a key step in the management of TB patients and in the preve
Comparison for the effects of different components of temperature variability on mortality: a multi-country time-series study (Publications)
BACKGROUND: Temperature variability (TV) is associated with increased mortality risk. However, it is still unknown whether intra-day or inter-day TV has different effects. OBJECTIVES: We aimed to asse
Ambient pollen exposure and pollen allergy symptom severity in the EPOCHAL study (Publications)
BACKGROUND: Ambient pollen exposure causes nasal, ocular, and pulmonary symptoms in allergic individuals, but the shape of the exposure-response association is not well characterized. We evaluated thi
Prospects and perspectives of health impact assessment: a systematic review of the peer-reviewed literature from june 2007 to january 2023 (Publications)
Objectives: In 2008, an analysis investigating health impact assessment (HIA) practice found that only 6% of HIA-related peer-reviewed publications had a focus on low- and medium-developed countries,
Systems thinking for supply chains: identifying bottlenecks using process mapping of a child health intervention in the Democratic Republic of the... (Publications)
The quality of supply chains in public health interventions in low- and middle-income countries can determine how effectively a program is able to treat its intended population group and subsequently