Gestational age acceleration is associated with epigenetic biomarkers of prenatal physiologic stress exposure (Publications)
BACKGROUND: Physiological maternal stress response, such as imbalance in the glucocorticoid pathway and immune system seems to be mediated by DNA methylation (DNAm) and might translate intrauterine st
Barriers to evidence use for sustainability: insights from pesticide policy and practice (Publications)
Calls for supporting sustainability through more and better research rest on an incomplete understanding of scientific evidence use. We argue that a variety of barriers to a transformative impact of e
Association of urinary and ambient black carbon, and other ambient pollutants with risk of prediabetes and metabolic syndrome in children and... (Publications)
The effects of exposure to black carbon (BC) on various diseases remains unclear, one reason being potential exposure misclassification following modelling of ambient air pollution levels. Urinary BC
Performance of antigen detection for HRP2-based malaria rapid diagnostic tests in community surveys: Tanzania, July-November 2017 (Publications)
BACKGROUND: Malaria rapid diagnostic tests (RDTs) based on the detection of the Plasmodium falciparum histidine-rich protein 2 (HRP2) antigen are widely used for detection of active infection with thi
Gene Coverage Count and Classification (GC3): a locus sequence coverage assessment tool using short-read whole genome sequencing data, and its... (Publications)
BACKGROUND: The ability of malaria rapid diagnostic tests (RDTs) to effectively detect active infections is being compromised by the presence of malaria strains with genomic deletions at the hrp2 and
The use of routine health facility data for micro-stratification of malaria risk in mainland Tanzania (Publications)
BACKGROUND: Current efforts to estimate the spatially diverse malaria burden in malaria-endemic countries largely involve the use of epidemiological modelling methods for describing temporal and spati
Selective anti-leishmanial strathclyde minor groove binders using an N-oxide tail-group modification (Publications)
The neglected tropical disease leishmaniasis, caused by Leishmania spp., is becoming more problematic due to the emergence of drug-resistant strains. Therefore, new drugs to treat leishmaniasis, with
Relatives from hereditary breast and ovarian cancer and lynch syndrome families forgoing genetic testing: findings from the Swiss CASCADE cohort (Publications)
Cascade genetic testing of relatives from families with pathogenic variants associated with hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) has important implications for cancer pre
Implementation approaches for leprosy prevention with single-dose rifampicin: a support tool for decision making (Publications)
BACKGROUND: In the past 15 years, the decline in annually detected leprosy patients has stagnated. To reduce the transmission of Mycobacterium leprae, the World Health Organization recommends single-d