Development of praziquantel sulphonamide derivatives as antischistosomal drugs (Publications)
The almost empty armamentarium to treat schistosomiasis, a neglected parasitic disorder caused by trematode flatworms of the genus Schistosoma, except Praziquantel (PZQ), urged to find new alternative
Greenspace’s value orientations of ecosystem service and socioeconomic service in China (Publications)
Background: Natural ecosystems provide necessary services for human beings, including ecosystem service values (ESVs) and socioeconomic service values (SSVs). The value orientations of ESVs and SSVs a
Is grip strength linked to body composition and cardiovascular risk markers in primary schoolchildren? Cross-sectional data from three African... (Publications)
OBJECTIVES: Muscular strength represents a specific component of health-related fitness. Hand grip strength (HGS) is used as an indicator for musculoskeletal fitness in children. HGS can also be used
Leveraging mathematical models of disease dynamics and machine learning to improve development of novel malaria interventions (Publications)
BACKGROUND: Substantial research is underway to develop next-generation interventions that address current malaria control challenges. As there is limited testing in their early development, it is dif
Microbiological characterisation of community-acquired urinary tract infections in Bagamoyo, Tanzania: a prospective study (Publications)
Urinary tract infections (UTIs) are among the most common infections in sub-Saharan Africa, but microbiological data to guide treatment decisions are limited. Hence, we investigated the bacterial aeti
Performance characteristics of next-generation sequencing for the detection of antimicrobial resistance determinants in <em>Escherichia coli... (Publications)
Short-read sequencing can provide detection of multiple genomic determinants of antimicrobial resistance from single bacterial genomes and metagenomic samples. Despite its increasing application in hu
Rethinking human resources and capacity building needs for malaria control and elimination in Africa (Publications)
Despite considerable success in controlling malaria worldwide, progress toward achieving malaria elimination has largely stalled. In particular, strategies to overcome roadblocks in malaria control an
Scalable process for high-yield production of PfCyRPA using insect cells for inclusion in a malaria virosome-based vaccine candidate (Publications)
Plasmodium falciparum cysteine-rich protective antigen (PfCyRPA) has been identified as a promising blood-stage candidate antigen to include in a broadly cross-reactive malaria vaccine. In the last co