Comparative ex vivo activity of novel endoperoxides in multidrug-resistant <em>Plasmodium falciparum</em> and <em>P. vivax</em> (Publications)
The declining efficacy of artemisinin derivatives against Plasmodium falciparum highlights the urgent need to identify alternative highly potent compounds for the treatment of malaria. In Papua Indone
Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study (Publications)
ABSTRACT: BACKGROUND: We describe the long-term outcome after clinical introduction and dose escalation of somatostatin receptor targeted therapy with [90Y-DOTA]-TOC in patients with metastasized neur
Assessing health impacts in complex eco-epidemiological settings in the humid tropics: advancing tools and methods (Publications)
In the developing world. large-scale projects in the extractive industry and natural resources sectors are often controversial and associated with long-term adverse health consequences to local commun
Novel <em>Bacteroides</em> host strains for detection of human- and animal-specific bacteriophages in water (Publications)
Bacteriophages active against specific Bacteroides host strains were shown to be suitable for detection of human faecal pollution. However, the practical application of this finding is limited because
Imidazolopiperazines: hit to lead optimization of new antimalarial agents (Publications)
Starting from a hit series from a GNF compound library collection and based on a cell-based proliferation assay of Plasmodium falciparum, a novel imidazolopiperazine scaffold was optimized. SAR for th
