Field comparison of circulating antibody assays <em>versus</em> circulating antigen assays for the detection of <em>Schistosomiasis japonica</em> in... (Publications)
BACKGROUND: Schistosomiasis remains a serious public health problem in affected countries, and routine, highly sensitive and cost-effective diagnostic methods are lacking. We evaluated two immunodiagn
Experimental infection of the pig with <em>Mycobacterium ulcerans</em>: a novel model for studying the pathogenesis of Buruli ulcer disease (Publications)
BACKGROUND: Buruli ulcer (BU) is a slowly progressing, necrotising disease of the skin caused by infection with Mycobacterium ulcerans. Non-ulcerative manifestations are nodules, plaques and oedema, w
<em>Plasmodium falciparum </em>infection and clinical indicators in relation to net coverage in central Côte d'Ivoire (Publications)
BACKGROUND: Sleeping under a net, particularly a long-lasting insecticidal net (LLIN), is associated with reduced malaria morbidity and mortality, but requires high coverage and adherence. In this stu
An experimental hut study to quantify the effect of DDT and airborne pyrethroids on entomological parameters of malaria transmission (Publications)
BACKGROUND: Current malaria vector control programmes rely on insecticides with rapid contact toxicity. However, spatial repellents can also be applied to reduce man-vector contact, which might ultima
Clustering of vector control interventions has important consequences for their effectiveness: a modelling study (Publications)
Vector control interventions have resulted in considerable reductions in malaria morbidity and mortality. When universal coverage cannot be achieved for financial or logistical reasons, the spatial ar
Effect of deworming on school-aged children's physical fitness, cognition and clinical parameters in a malaria-helminth co-endemic area of Côte... (Publications)
BACKGROUND: Malaria and helminth infections are thought to negatively affect children's nutritional status and to impair their physical and cognitive development. Yet, the current evidence-base is wea
Effect of home-based counselling on newborn care practices in southern Tanzania one year after implementation: a cluster-randomised controlled trial (Publications)
BACKGROUND: In Sub-Saharan Africa over one million newborns die annually. We developed a sustainable and scalable home-based counselling intervention for delivery by community volunteers in rural sout
Prevalence and spatial distribution of<em> Theileria parva</em> in cattle under crop-livestock farming systems in Tororo district, eastern Uganda (Publications)
BACKGROUND: Tick-borne diseases (TBDs) present a major economic burden to communities across East Africa. Farmers in East Africa must use acaracides to target ticks and prevent transmission of tick-bo