Early manifestations (pre-AIDS) of HIV-1 infection in Uganda (Publications)
OBJECTIVES: To describe the early manifestations of HIV-1 infection before the development of AIDS, in a rural Ugandan population. METHODS: Three monthly follow-up of HIV-1-infected and uninfected par
Abnormal blood glucose concentrations on admission to a rural Kenyan district hospital: prevalence and outcome (Publications)
AIMS: To determine the prevalence, clinical characteristics, and outcome of hypoglycaemia on admission in children at a rural Kenyan district hospital. METHODS: Observational study of 3742 children (i
Reduced fertility associated with HIV: the contribution of pre-existing subfertility (Publications)
BACKGROUND: HIV-1 infection is associated with lower fertility among women in sub-Saharan Africa and this association is not explained by the frequency of sexual intercourse, illness, knowledge of HIV
Comparison of axillary, rectal and tympanic temperature measurements in children admitted with malaria (Publications)
We compared axillary, rectal and tympanic temperatures in children admitted with severe malaria. The axillary temperatures were 0.74 degrees C (95% limits of agreement -0.85 to 2.33 degrees C) less th
Causes of death in a rural, population-based human immunodeficiency virus type 1 (HIV-1) natural history cohort in Uganda (Publications)
BACKGROUND: While human immunodeficiency virus (HIV)-related causes of death have been well documented in developed countries, in Africa data are scanty and mainly based on autopsy studies from city h
Outcome of delivery and cause-specific mortality and severe morbidity in early infancy: a Kenyan District Hospital birth cohort (Publications)
It has proven very difficult to determine the causes of early infant mortality and morbidity in Africa. We undertook a two-year, prospective birth cohort study in a rural Kenyan District Hospital to e
HIV-1 RNA levels in an African population-based cohort and their relation to CD4 lymphocyte counts and World Health Organization clinical staging (Publications)
Apart from a small number of reports from people who are based in hospitals, data on viral load in HIV-infected people in sub-Saharan Africa, where most infections occur, are lacking. We report serum
Relationship between HIV-1 Env subtypes A and D and disease progression in a rural Ugandan cohort (Publications)
OBJECTIVE: To investigate the role of HIV-1 envelope subtypes on disease progression in a rural cohort of Ugandan adults where two major HIV-1 subtypes (A and D) exist. METHODS: Participants of a clin