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1. The antitrypanosomal and antitubercular activity of some nitro(triazole/imidazole)-based aromatic amines (Publications)

   The antitrypanosomal and antitubercular activity of some nitro(triazole/imidazole)-based aromatic amines

   Relevance:

   A limited number of novel 3-nitrotriazole- and 2-nitroimidazole-linked quinolines and quinazolines were synthesized and screened for in vitro antitrypanosomal and antitubercular activities as well as

2. Antimalarial inhibitors targeting serine hydroxymethyltransferase (SHMT) with <em>in vivo</em> efficacy and analysis of their binding mode based on... (Publications)

   Antimalarial inhibitors targeting serine hydroxymethyltransferase (SHMT) with <em>in vivo</em> efficacy and analysis of their binding mode based on X-ray cocrystal structures

   Relevance:

   Target-based approaches toward new antimalarial treatments are highly valuable to prevent resistance development. We report several series of pyrazolopyran-based inhibitors targeting the enzyme serine

3. Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis (Publications)

   Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis

   Relevance:

   BACKGROUND: The criteria for defining severe malaria have evolved over the last 20 years. We aimed to assess the strength of association of death with features currently characterizing severe malaria

4. 3-hydroxy-N'-arylidenepropanehydrazonamides with halo-substituted phenanthrene scaffolds cure <em>P. berghei</em> infected mice when administered... (Publications)

   3-hydroxy-N'-arylidenepropanehydrazonamides with halo-substituted phenanthrene scaffolds cure <em>P. berghei</em> infected mice when administered perorally

   Relevance:

   Structural optimization of 3-hydroxy-N'-arylidenepropanehydrazonamides provided new analogs with nanomolar to subnanomolar antiplasmodial activity against asexual blood stages of Plasmodium falciparum

5. The Mini-FLOTAC technique for the diagnosis of helminth and protozoan infections in humans and animals (Publications)

   The Mini-FLOTAC technique for the diagnosis of helminth and protozoan infections in humans and animals

   Relevance:

   This protocol is an extension to: Nat. Protoc. 5, 503-515 (2010); doi: 10.1038/nprot.2009.235; published online 25 February 2010The FLOTAC is a sensitive, accurate, and precise technique for the diagn

6. Patient-identified priorities leading to attempted suicide (Publications)

   Patient-identified priorities leading to attempted suicide

   Relevance:

   BACKGROUND: Attempted suicide is a major public health problem. AIM: The aim of this study was to identify patient-identified problems and triggers typically leading to attempted suicide. METHOD: A re

7. First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: a meta-analysis of... (Publications)

   First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: a meta-analysis of observational studies

   Relevance:

   BACKGROUND: Animal embryotoxicity data, and the scarcity of safety data in human pregnancies, have prevented artemisinin derivatives from being recommended for malaria treatment in the first trimester

8. Epidemiology, spatial distribution and control of <em>Schistosomiasis mansoni</em> in western Côte D'Ivoire (Publications)

   Epidemiology, spatial distribution and control of <em>Schistosomiasis mansoni</em> in western Côte D'Ivoire

   Relevance:

9. Defining health research for development: the perspective of stakeholders from an international health research partnership in Ghana and Tanzania (Publications)

   Defining health research for development: the perspective of stakeholders from an international health research partnership in Ghana and Tanzania

   Relevance:

   OBJECTIVES: The study uses a qualitative empirical method to define Health Research for Development. This project explores the perspectives of stakeholders in an international health research partners

10. Accuracy of diagnostic tests for <em>Schistosoma mansoni</em> infection in asymptomatic Eritrean refugees: serology and POC-CCA against stool... (Publications)

    Accuracy of diagnostic tests for <em>Schistosoma mansoni</em> infection in asymptomatic Eritrean refugees: serology and POC-CCA against stool microscopy

    Relevance:

    Background: The unprecedented increase in number of African refugees arriving in Europe is confronting clinicians and general practitioners with the question of whether or not and how to screen migran