KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment and prevention of disease transmission (Publications)
Renewed global efforts toward malaria eradication have highlighted the need for novel antimalarial agents with activity against multiple stages of the parasite life-cycle. We have previously reported
Female predominance and transmission distortion in the long-QT syndrome (Publications)
BACKGROUND: Congenital long-QT syndrome is a disorder resulting in ventricular arrhythmias and sudden death. The most common forms of the long-QT syndrome, types 1 and 2, are caused by mutations in th
Effect of ibandronate on spontaneous osteonecrosis of the knee: a randomized, double-blind, placebo-controlled trial (Publications)
Based on this double-blind, placebo-controlled study, ibandronate has no beneficial effect on clinical and radiological outcome in patients with spontaneous osteonecrosis of the knee over and above an
Reasons for false-positive lipoarabinomannan ELISA results in a Tanzanian population [Short communication] (Publications)
Lipoarabinomannan (LAM), a cell wall component of mycobacteria, can be detected in the urine of tuberculosis (TB) patients. Advantages of this diagnostic include the ease of sample collection and test
Drugs for treating <em>Schistosoma mansoni</em> infection (Publications)
BACKGROUND: Schistosoma mansoni is a parasitic infection common in the tropics and sub-tropics. Chronic and advanced disease includes abdominal pain, diarrhoea, blood in the stool, liver cirrhosis, po
Self-rated health: small area large area comparisons amongst older adults at the state, district and sub-district level in India (Publications)
We compared prevalence estimates of self-rated health (SRH) derived indirectly using four different small area estimation methods for the Vadu (small) area from the national Study on Global AGEing (SA
Maurer's clefts, the enigma of <em>Plasmodium falciparum</em> (Publications)
Plasmodium falciparum, the causative agent of malaria, completely remodels the infected human erythrocyte to acquire nutrients and to evade the immune system. For this process, the parasite exports mo