A role for apical membrane antigen 1 during invasion of hepatocytes by <em>Plasmodium falciparum</em> sporozoites (Publications)
Plasmodium sporozoites are transmitted through the bite of infected mosquitoes and invade hepatocytes, as a first and obligatory step of the parasite life cycle in man. Hepatocyte invasion involves pr
Effectiveness of artemether/lumefantrine for the treatment of uncomplicated <em>Plasmodium vivax</em> and <em>P. falciparum</em> malaria in young... (Publications)
Background. Artemisinin combination therapy (ACT) is recommended as treatment for uncomplicated Plasmodium falciparum (Pf) malaria, while chloroquine is still widely used for non-Pf infections. A comm
The economic cost to households of childhood malaria in Papua New Guinea: a focus on intra-country variation (Publications)
BACKGROUND We compare direct and indirect household costs associated with malaria treatment for children
Compounds structurally related to ellagic acid show improved antiplasmodial activity (Publications)
The cancer chemopreventive agent ellagic acid (EA) is a known inhibitor of glutathione S-transferases (GSTs) and possesses antiplasmodial activities in the upper-nanomolar range. In the recent drug de
Single nucleotide polymorphisms in <em>Mycobacterium tuberculosis</em> and the need for a curated database (Publications)
Recent advances in DNA sequencing have led to the discovery of thousands of single nucleotide polymorphisms (SNPs) in clinical isolates of Mycobacterium tuberculosis complex (MTBC). This genetic varia
Continuous video-EEG monitoring increases detection rate of nonconvulsive status epilepticus in the ICU (Publications)
Purpose: Status epilepticus (SE) is an important neurologic emergency requiring treatment on an intensive care unit (ICU). Although convulsive SE is self-evident, the diagnosis of nonconvulsive SE (NC
Acute phase proteins and white blood cell levels for prediction of infectious complications in status epilepticus (Publications)
ABSTRACT: INTRODUCTION: Infections in status epilepticus (SE) patients result in severe morbidity making early diagnosis crucial. As SE may lead to inflammatory reaction, the value of acute phase prot