Human T cell epitopes of <em>Mycobacterium tuberculosis</em> are evolutionarily hyperconserved (Publications)
Mycobacterium tuberculosis is an obligate human pathogen capable of persisting in individual hosts for decades. We sequenced the genomes of 21 strains representative of the global diversity and six ma
A role for systems epidemiology in tuberculosis research (Publications)
Despite being a curable disease, tuberculosis (TB) killed more people in 2009 than during any previous year in history. Progress in TB research has been slow, and remains burdened by important gaps in
Oral treatment for <em>Mycobacterium ulcerans</em> infection: results from a pilot study in Benin (Publications)
Mycobacterium ulcerans infection is responsible for severe skin lesions in sub-Saharan Africa. We enrolled 30 Beninese patients with Buruli ulcers in a pilot study to evaluate efficacy of an oral chem
Incidence of asthma and net change in symptoms in relation to changes in obesity (Publications)
The incidence of asthma has been reported to be associated with obesity. An alternative analysis, of net change in prevalence, does not require exclusion of those with asthma at baseline.Follow-up dat
Honeys from different floral sources as inhibitors of enzymatic browning in fruit and vegetable homogenates (Publications)
Honeys from different floral sources were evaluated for their antioxidant content and for their ability to inhibit enzymatic browning in fruits and vegetables. Antioxidant contents of honeys vary wide
Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS) (Publications)
BACKGROUND: Traffic-related air pollution is related with asthma, and this association may be modified by genetic factors. OBJECTIVES: We investigated the role of genetic polymorphisms potentially mod
What defines airflow obstruction in asthma? (Publications)
Asthma guidelines from the Global Initiative for Asthma (GINA) and from the National Heart, Lung, and Blood Institute provide conflicting definitions of airflow obstruction, suggesting a fixed forced