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1. Strong interferon-gamma mediated cellular immunity to scrub typhus demonstrated using a novel whole cell antigen ELISpot assay in rhesus macaques and... (Publications)

   Strong interferon-gamma mediated cellular immunity to scrub typhus demonstrated using a novel whole cell antigen ELISpot assay in rhesus macaques and humans

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   Scrub typhus is a febrile infection caused by the obligate intracellular bacterium Orientia tsutsugamushi, which causes significant morbidity and mortality across the Asia-Pacific region. The control

2. The Global Burden of Disease Study 2013: what does it mean for the NTDs? (Publications)

   The Global Burden of Disease Study 2013: what does it mean for the NTDs?

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3. A stochastic model for the probability of malaria extinction by mass drug administration (Publications)

   A stochastic model for the probability of malaria extinction by mass drug administration

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4. Antimalarial inhibitors targeting serine hydroxymethyltransferase (SHMT) with <em>in vivo</em> efficacy and analysis of their binding mode based on... (Publications)

   Antimalarial inhibitors targeting serine hydroxymethyltransferase (SHMT) with <em>in vivo</em> efficacy and analysis of their binding mode based on X-ray cocrystal structures

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   Target-based approaches toward new antimalarial treatments are highly valuable to prevent resistance development. We report several series of pyrazolopyran-based inhibitors targeting the enzyme serine

5. Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis (Publications)

   Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis

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   BACKGROUND: The criteria for defining severe malaria have evolved over the last 20 years. We aimed to assess the strength of association of death with features currently characterizing severe malaria

6. 3-hydroxy-N'-arylidenepropanehydrazonamides with halo-substituted phenanthrene scaffolds cure <em>P. berghei</em> infected mice when administered... (Publications)

   3-hydroxy-N'-arylidenepropanehydrazonamides with halo-substituted phenanthrene scaffolds cure <em>P. berghei</em> infected mice when administered perorally

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   Structural optimization of 3-hydroxy-N'-arylidenepropanehydrazonamides provided new analogs with nanomolar to subnanomolar antiplasmodial activity against asexual blood stages of Plasmodium falciparum

7. The Mini-FLOTAC technique for the diagnosis of helminth and protozoan infections in humans and animals (Publications)

   The Mini-FLOTAC technique for the diagnosis of helminth and protozoan infections in humans and animals

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   This protocol is an extension to: Nat. Protoc. 5, 503-515 (2010); doi: 10.1038/nprot.2009.235; published online 25 February 2010The FLOTAC is a sensitive, accurate, and precise technique for the diagn

8. Patient-identified priorities leading to attempted suicide (Publications)

   Patient-identified priorities leading to attempted suicide

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   BACKGROUND: Attempted suicide is a major public health problem. AIM: The aim of this study was to identify patient-identified problems and triggers typically leading to attempted suicide. METHOD: A re

9. First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: a meta-analysis of... (Publications)

   First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: a meta-analysis of observational studies

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   BACKGROUND: Animal embryotoxicity data, and the scarcity of safety data in human pregnancies, have prevented artemisinin derivatives from being recommended for malaria treatment in the first trimester

10. Epidemiology, spatial distribution and control of <em>Schistosomiasis mansoni</em> in western Côte D'Ivoire (Publications)

    Epidemiology, spatial distribution and control of <em>Schistosomiasis mansoni</em> in western Côte D'Ivoire

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