Mixed Th1 and Th2 <em>Mycobacterium tuberculosis</em>-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania (Publications)
Mycobacterium tuberculosis (Mtb) and helminth infections elicit antagonistic immune effector functions and are co-endemic in several regions of the world. We therefore hypothesized that helminth infec
Understanding resilience of female adolescents towards teenage pregnancy: a cross-sectional survey in Dar es Salaam, Tanzania (Publications)
BACKGROUND: In Tanzania, teenage pregnancy rates are still high despite the efforts being made to reduce them. Not enough is known about how adolescents experience and cope with sexuality and teenage
Antischistosomal activity of pyrido[1,2-a]benzimidazole derivatives and correlation with inhibition of beta-hematin formation (Publications)
The extensive use of praziquantel against schistosomiasis raises concerns about drug resistance. New therapeutic alternatives targeting critical pathways within the parasite are therefore urgently nee
High awareness but low coverage of a locally produced fortified complementary food in Abidjan, Côte d'Ivoire: findings from a cross-sectional... (Publications)
Poor complementary feeding practices among infants and young children in Cote d'Ivoire are major contributing factors to the country's high burden of malnutrition. As part of a broad effort to address
Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa (Publications)
BACKGROUND: Anaemia is common in malaria. It is important to quantitate the risk of anaemia and to distinguish factors related to the natural history of disease from potential drug toxicity. METHODS:
Natural immune response to <em>Plasmodium vivax </em>alpha-helical coiled coil protein motifs and its association with the risk of <em>P. vivax</em>... (Publications)
Protein alpha-helical coiled coil structures are known to induce antibodies able to block critical functions in different pathogens. In a previous study, a total of 50 proteins of Plasmodium vivax ery
The within-host population dynamics of <em>Mycobacterium tuberculosi</em>s vary with treatment efficacy (Publications)
BACKGROUND: Combination therapy is one of the most effective tools for limiting the emergence of drug resistance in pathogens. Despite the widespread adoption of combination therapy across diseases, d
