Polyamidoamine nanoparticles for the oral administration of antimalarial drugs (Publications)
Current strategies for the mass administration of antimalarial drugs demand oral formulations to target the asexual Plasmodium stages in the peripheral bloodstream, whereas recommendations for future
Does test-based prescription of evidence-based treatment for malaria improve treatment seeking and satisfaction? Findings of repeated cross-sectional... (Publications)
Introduction: The presumptive treatment of febrile illness with antimalarial medication is becoming less common in low-income and middle-income countries as access to reliable diagnostic tests improve
Laboratory-reflex cryptococcal antigen screening is associated with a survival benefit in Tanzania (Publications)
BACKGROUND: Cryptococcal antigen (CrAg) screening in persons with advanced HIV/AIDS is recommended to prevent death. Implementing CrAg screening only in outpatients may underestimate the true CrAg pre
Point-of-Care-Ultraschall: Lehren und Lernen in Ifakara, Tansania (Publications)
Point-of-Care Ultrasound: Teaching and Learning in Ifakara, Tanzania Abstract. Presentation of two practical cases from the point-of-care ultrasound class in Ifakara, Tanzania. The first case shows th
Changes in serum creatinine concentration and acute kidney injury (aki) grade in dogs treated with hydroxyethyl starch 130/0.4 from 2013 to 2015 (Publications)
BACKGROUND: Hydroxyethyl starch (HES) solutions may cause acute kidney injury (AKI) in humans. OBJECTIVE: To compare AKI grades in 94 dogs exposed and 90 dogs that were unexposed to 6% HES-130/0.4. AN
Complementary quantitative structure(-)activity relationship models for the antitrypanosomal activity of sesquiterpene lactones (Publications)
Three complementary quantitative structure(-)activity relationship (QSAR) methodologies, namely, regression modeling based on (i) "classical" molecular descriptors, (ii) 3D pharmacophore features, and
Efficacy and safety of ascending dosages of tribendimidine against hookworm infections in children: a randomized controlled trial (Publications)
Background: The global strategy to control soil-transmitted helminthiasis is mainly focused on preventive chemotherapy based on albendazole and mebendazole. We assessed the efficacy and safety of asce
A multiplex assay for the sensitive detection and quantification of male and female <em>Plasmodium falciparum</em> gametocytes (Publications)
BACKGROUND: The transmission of malaria to mosquitoes depends on the presence of gametocytes that circulate in the peripheral blood of infected human hosts. Sensitive estimates of the densities of fem