Behavior of sunbed users in Switzerland (Publications)
OBJECTIVES: A constant rise in the number of skin cancer cases has been observed during the last few years. An important reason for this trend is that exposure of the population to UV radiation is hig
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials (Publications)
AIMS: To asses the safety and pharmacokinetics of a new synthetic ozonide antimalarial, OZ439, in a first-in-man, double-blind study in healthy volunteers. METHODS: OZ439 was administered as single or
Melarsoprol refractory <em>T. b. gambiense</em> from Omugo, north-western Uganda (Publications)
Culture adapted T. b. gambiense isolated from Northwest Uganda were exposed to 0.001-0.14 microg/ml melarsoprol or 1.56-100 microg/ml DL-alpha-difluoromethylornithine (DFMO). Minimum inhibitory concen
A nucleoside transporter from <em>Trypanosoma brucei</em> involved in drug resistance (Publications)
Drug resistance of pathogens is an increasing problem whose underlying mechanisms are not fully understood. Cellular uptake of the major drugs against Trypanosoma brucei spp., the causative agents of
Ökonomische Nutzen und Kosten populationsbezogener Prävention und Gesundheitsförderung (Publications)
Objectives: It is a generally accepted requirement that disease and accident prevention as well as health promotion should be both effective and accomplished at minimum cost. The aim of this study is
Placental infection with <em>Plasmodium vivax</em>: a histopathological and molecular study (Publications)
Background. Evidence of the presence of Plasmodium vivax in the placenta is scarce and inconclusive. This information is relevant to understanding whether P. vivax affects placental function and how i