Comparative palatability of orally disintegrating tablets (ODTs) of praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: a... (Publications)
BACKGROUND: Praziquantel (PZQ) is currently the only recommended drug for infection and disease caused by the schistosome species that infects humans; however, the current tablet formulation is not su
Characterization of moxidectin against <em>Strongyloides ratti:</em> <em>in vitro</em> and<em> in vivo </em>activity and pharmacokinetics in the rat... (Publications)
Strongyloides stercoralis is a soil-transmitted helminth affecting an estimated 30-100 million people. Since the infection may be severe and life-threatening, accessible and effective treatment is piv
Spatial epidemiology of urban health risks in select West African cities (Publications)
West African cities face critical societal challenges that are linked to environmental and health changes. These challenges are further exacerbated by urbanization dynamics, climate change, socio-econ
Cytochrome P450-mediated metabolism and CYP Inhibition for the synthetic peroxide antimalarial OZ439 (Publications)
OZ439 is a potent synthetic ozonide evaluated for the treatment of uncomplicated malaria. The metabolite profile of OZ439 was characterized in vitro using human liver microsomes combined with LC/MS-MS
Determinants of safety climate at primary care level in Ghana, Malawi and Uganda: a cross-sectional study across 138 selected primary healthcare... (Publications)
BACKGROUND: Safety climate is an essential component of achieving Universal Health Coverage, with several organisational, unit or team-level, and individual health worker factors identified as influen
The role of extreme temperature in cause-specific acute cardiovascular mortality in Switzerland: a case-crossover study (Publications)
Since the 2003 heatwave in Europe, evidence has been rapidly increasing on the association between extreme temperature and all-cause mortality. Little is known, however, about cause-specific cardiovas
Synthesis, <em>in vitro</em> antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles (Publications)
A series of monocationic new guanidinobenzimidazole derivatives were prepared in a four step process starting from 2-nitro-1,4-phenylendiamine. Their antiparasitic activity against Plasmodium falcipar
Health impacts of industrial mining on surrounding communities: local perspectives from three sub-Saharan African countries (Publications)
Industrial mining projects can play an important role in global sustainable development if associated health risks are minimised and opportunities maximised. While a broad body of evidence from quanti
Spatio-temporal modelling of changes in air pollution exposure associated to the COVID-19 lockdown measures across Europe (Publications)
The lockdown and related measures implemented by many European countries to stop the spread of the SARS-CoV-2 virus (COVID-19) pandemic have altered the economic activities and road transport in many
Rabies in sub-Sahara Africa: One Health-based surveillance strategy in the Kongo Central province (Democratic Republic of the Congo) and disease... (Publications)
Rabies is a viral zoonotic disease transmitted to humans in more than 99% of cas-es through the bite or scratch of an infected dog (dog-mediated rabies).To date all countries on the sub-Saharan Africa
