Medicinal chemistry optimization of a diaminopurine chemotype: toward a lead for <em>Trypanosoma brucei</em> inhibitors (Publications)
Human African trypanosomiasis (HAT), or sleeping sickness, is caused by the protozoan parasite Trypanosoma brucei and transmitted through the bite of infected tsetse flies. The disease is considered f
Registration and local production of essential medicines in Uganda (Publications)
Background: Universal access to high quality essential medicines is critical to sustainable development (SDG 3.8). However low- and middle-income countries struggle to ensure access to all medicines o
Cross-reaction of POC-CCA urine test for detection of <em>Schistosoma mekongi</em> in Lao PDR: a cross-sectional study (Publications)
BACKGROUND: The point-of-care circulating cathodic antigen (POC-CCA) test is increasingly used as a rapid diagnostic method for Schistosoma mansoni infection. The test has good sensitivity, although f
Urogenital schistosomiasis in fisherman, Nepal, 2019 (Publications)
We report a case of urogenital schistosomiasis in a 34-year-old male patient in Nepal and summarize additional case reports. These cases provide putative evidence for the potential existence of human-
Estimated whole-brain and lobe-specific radiofrequency electromagnetic fields doses and brain volumes in preadolescents (Publications)
OBJECTIVE: To assess the association between estimated whole-brain and lobe-specific radiofrequency electromagnetic fields (RF-EMF) doses, using an improved integrated RF-EMF exposure model, and brain
An autoencoder and artificial neural network-based method to estimate parity status of wild mosquitoes from near-infrared spectra (Publications)
After mating, female mosquitoes need animal blood to develop their eggs. In the process of acquiring blood, they may acquire pathogens, which may cause different diseases in humans such as malaria, zi
Health system's response to the COVID-19 pandemic in conflict settings: policy reflections from Palestine (Publications)
As the COVID-19 pandemic spreads, concerns are particularly serious in conflict and humanitarian settings. Tackling the pandemic in those countries is challenging due to the fragility of socioeconomic
Layering and scaling up chronic non-communicable disease care on existing HIV care systems and acute care settings in Kenya: a cost and budget impact... (Publications)
INTRODUCTION: Like many countries in sub-Saharan Africa, Kenya is experiencing a rapid rise in the burden of non-communicable diseases (NCDs): NCDs now contribute to over 50% of inpatient admissions a
On the island of Zanzibar people in the community are frequently colonized with the same MDR Enterobacterales found in poultry and retailed chicken... (Publications)
OBJECTIVES: Intestinal colonization with extended-spectrum cephalosporin-resistant (ESC-R) and colistin-resistant (CST-R) Enterobacterales (Ent) can be driven by contact with colonized animals and/or
