HIV infection disrupts the sympatric host-pathogen relationship in human tuberculosis (Publications)
The phylogeographic population structure of Mycobacterium tuberculosis suggests local adaptation to sympatric human populations. We hypothesized that HIV infection, which induces immunodeficiency, wil
Guidance for evidence-informed policies about health systems: rationale for and challenges of guidance development (Publications)
In the first paper in a three-part series on health systems guidance, Xavier Bosch-Capblanch and colleagues examine how guidance is currently formulated in low- and middle-income countries, and the ch
Reduction in the proportion of fevers associated with <em>Plasmodium falciparum</em> parasitaemia in Africa: a systematic review (Publications)
BACKGROUND: Malaria is almost invariably ranked as the leading cause of morbidity and mortality in Africa. There is growing evidence of a decline in malaria transmission, morbidity and mortality over
Accuracy of urine circulating cathodic antigen (CCA) test for <em>Schistosoma mansoni</em> diagnosis in different settings of Côte d'Ivoire (Publications)
BACKGROUND: Promising results have been reported for a urine circulating cathodic antigen (CCA) test for the diagnosis of Schistosoma mansoni. We assessed the accuracy of a commercially available CCA
Eukaryotic translation elongation factor 1A (eEF1A) domain I from <em>S. cerevisiae</em> is required but not sufficient for inter-species... (Publications)
Ethanolamine phosphoglycerol (EPG) is a protein modification attached exclusively to eukaryotic elongation factor 1A (eEF1A). In mammals and plants, EPG is linked to conserved glutamate residues locat