Schistosomiasis at the crossroad to elimination: review of eclipsed research with emphasis on the post-transmission agenda (Publications)
While chronic schistosomiasis is pathologically well defined, the acute form of the disease is less well understood. It is generally agreed that early lesions, such as lung nodules and bladder polyps,
Whole-organism phenotypic screening methods used in early-phase anthelmintic drug discovery (Publications)
Diseases caused by parasitic helminths (worms) represent a major global health burden in both humans and animals. As vaccines against helminths have yet to achieve a prominent role in worm control, an
Point-of-care sample preparation and automated quantitative detection of <em>Schistosoma haematobium </em>using mobile phone microscopy (Publications)
Schistosoma haematobium continues to pose a significant public health burden despite ongoing global control efforts. One of several barriers to sustained control (and ultimately elimination) is the la
Discovery of novel antischistosomal scaffolds from the open access Pandemic Response Box (Publications)
BACKGROUND: Treatment and control of schistosomiasis rely on a single drug, praziquantel. New orally active antischistosomals featuring novel molecular scaffolds are urgently needed to prevent the eme
Sustainability of a school-based health intervention for prevention of non-communicable diseases in marginalised communities: protocol for a... (Publications)
INTRODUCTION: The prevalence of chronic, lifestyle-related diseases is increasing among adults and children from low-income and middle-income countries. Despite the effectiveness of community-based in
More than seven decades of <em>Acta Tropica</em>: partnership to advance the 2030 Agenda for Sustainable Development (Publications)
The inaugural issue of Acta Tropica has been published in 1944, at a time of utmost international isolation and uncertainty due to World War II. Now, more than seven decades later, Acta Tropica is a t
From reverse innovation to global innovation in animal health: a review (Publications)
Reverse innovation refers to learning from or diffusion of innovations developed in low income settings and further translated to industrialized countries. There is lack of consensus regarding termino
Viral suppression after transition from nonnucleoside reverse transcriptase inhibitor- to dolutegravir-based antiretroviral therapy: a prospective... (Publications)
OBJECTIVES: Since 2018, the World Health Organization has recommended dolutegravir (DTG)-containing antiretroviral therapy (ART) for most people living with HIV. Country programmes across Africa have
More than seven decades of <em>Acta Tropica</em>: looking back to move into the future (Publications)
Acta Tropica is an international, peer-reviewed journal advancing scientific research in the fields of tropical medicine and parasitology. This article elucidates the rich history of the journal and s
Current use pesticides in soil and air from two agricultural sites in South Africa: implications for environmental fate and human exposure (Publications)
Concerns about the possible negative impacts of current use pesticides (CUPs) for both the environment and human health have increased worldwide. However, the knowledge on the occurrence of CUPs in so