A research agenda for malaria eradication: health systems and operational research (Publications)
Health systems research and development is needed to support the global malaria eradication agenda. In this paper, we (the malERA Consultative Group on Health Systems and Operational Research) focus o
Population-based screening - the difficulty of how to do more good than harm and how to achieve it (Publications)
Screening people without symptoms of disease is an attractive idea. Screening allows early detection of disease or elevated risk of disease, and has the potential for improved treatment and reduction
Molecular surveillance of the antifolateresistant mutation I164L in imported African isolates of <em>Plasmodium falciparum</em> in Europe: sentinel... (Publications)
BACKGROUND: Malaria parasites that carry the DHFR-mutation I164L are not only highly resistant to sulfadoxine-pyrimethamine but also to the new antimalarial drug chlorproguanil-dapsone. The spread of
Nuclear factor I genomic binding associates with chromatin boundaries (Publications)
BACKGROUND: The Nuclear Factor I (NFI) family of DNA binding proteins (also called CCAAT box transcription factors or CTF) is involved in both DNA replication and gene expression regulation. Using chr
Estimating <em>Plasmodium falciparum</em> transmission rates in low-endemic settings using a combination of community prevalence and health facility... (Publications)
As some malaria control programs shift focus from disease control to transmission reduction, there is a need for transmission data to monitor progress. At lower levels of transmission, it becomes incr
Sleeping sickness in travelers - do they really sleep? (Publications)
The number of imported Human African Trypanosomiasis (HAT) cases in non-endemic countries has increased over the last years. The objective of this analysis is to describe the clinical presentation of
Effect of sanitation on soil-transmitted helminth infection: systematic review and meta-analysis (Publications)
BACKGROUND: In countries of high endemicity of the soil-transmitted helminth parasites Ascaris lumbricoides, Trichuris trichiura, and hookworm, preventive chemotherapy (i.e., repeated administration o
The use of insecticide-treated nets for reducing malaria morbidity among children aged 6-59 months, in an area of high malaria transmission in central... (Publications)
ABSTRACT: BACKGROUND: Long-lasting insecticidal nets (LLINs) are an important tool for controlling malaria. Much attention has been devoted to determine both the effect of LLINs on the reduction of Pl
Solar drinking water disinfection (SODIS) to reduce childhood diarrhoea in rural Bolivia: a cluster-randomized, controlled trial (Publications)
BACKGROUND: Solar drinking water disinfection (SODIS) is a low-cost, point-of-use water purification method that has been disseminated globally. Laboratory studies suggest that SODIS is highly efficac
Intravaginal practices, vaginal infections and HIV acquisition: systematic review and meta-analysis (Publications)
BACKGROUND: Intravaginal practices are commonly used by women to manage their vaginal health and sexual life. These practices could, however, affect intravaginal mucosal integrity. The objectives of t
