Genetically modified malaria parasites as vaccine candidates (Publications)
Induction of sterile immunity against sporozoite and liver stages of malaria is a long-standing aim in vaccine development. Genetically engineered, attenuated sporozoites were systematically evaluated
A comparison of statistical and machine-learning approaches for spatiotemporal modeling of nitrogen dioxide across Switzerland (Publications)
Land use regression modeling has commonly been used to model ambient air pollutant concentrations in environmental epidemiological studies. Recently, other statistical and machine-learning methods hav
Stigma-directed services (Stig2Health) to improve 'linkage to care' for people living with HIV in rural Tanzania: study protocol for a nested pre-post... (Publications)
Background: HIV-related stigma is a major barrier to the timely linkage and retention of patients in HIV care in sub-Saharan Africa, where most people living with HIV/AIDS reside. In this implementati
Perceived water-related risk factors of Buruli ulcer in two villages of south-central Côte d’Ivoire (Publications)
Background Buruli ulcer, caused by Mycobacterium ulcerans, is a neglected tropical skin disease that is primarily endemic in West and Central Africa, including Côte d’Ivoire. Studies indicate that M.
Long-term exposure to traffic-related air pollution and stroke: a systematic review and meta-analysis (Publications)
Background Stroke remains the second cause of death worldwide. The mechanisms underlying the adverse association of exposure to traffic-related air pollution (TRAP) with overall cardiovascular disease
Care cascades for hypertension and diabetes: cross-sectional evaluation of rural districts in Tanzania (Publications)
BACKGROUND: Noncommunicable diseases (NCDs), especially hypertension and diabetes, are rapidly rising in sub-Saharan Africa, necessitating health systems transformations. In Tanzania, current policies
Should we treat <em>Blastocystis </em>sp.? A double-blind placebo-controlled randomized pilot trial (Publications)
BACKGROUND: Blastocystis sp. is a worldwide-distributed protist colonizing the guts of humans and a great variety of animals. It is unclear whether it is just a commensal or an infectious parasite tha
Informal support networks of Tanzanians with chronic diseases: predictors of support provision and treatment adherence (Publications)
Objectives: To examine the role of NCD patients' social ties as informal caregivers and whether receiving their support is associated with engagement in care. Methods: NCD outpatients (N(2) = 100) in
High levels of surgical antibiotic prophylaxis: implications for hospital-based antibiotic stewardship in Sierra Leone (Publications)
OBJECTIVE: Despite the impact of inappropriate prescribing on antibiotic resistance, data on surgical antibiotic prophylaxis in sub-Saharan Africa are limited. In this study, we evaluated antibiotic u
Tiergestützte Schmerztherapie: Hilfreich bei chronischen Schmerzen im Kindes- und Jugendalter? (Publications)
Kinder und Jugendliche, die an chronischen Schmerzen leiden, sind häufig schwer für therapeutische und Bewegungsangebote zu motivieren. Hier setzen tiergestützte Interventionen an. Bisherige Studiener
