Simulated impact of RTS,S/AS01 vaccination programs in the context of changing malaria transmission (Publications)
INTRODUCTION: The RTS,S/AS01 pre-erythrocytic malaria vaccine is in phase III clinical trials. It is critical to anticipate where and how it should be implemented if trials are successful. Such planni
Viral hepatitis and rapid diagnostic test based screening for HBsAg in HIV-infected patients in rural Tanzania (Publications)
BACKGROUND: Co-infection with hepatitis B virus (HBV) is highly prevalent in people living with HIV in Sub-Saharan Africa. Screening for HBV surface antigen (HBsAg) before initiation of combination an
Design, implementation and evaluation of a national campaign to distribute nine million free LLINs to children under five years of age in Tanzania (Publications)
ABSTRACT: BACKGROUND: After a national voucher scheme in 2004 provided pregnant women and infants with highly subsidized insecticide-treated nets (ITNs), use among children under five years (U5s) in m
Gender differences in disordered eating and weight dissatisfaction in Swiss adults: which factors matter? (Publications)
BACKGROUND: Research results from large, national population-based studies investigating gender differences in weight dissatisfaction and disordered eating across the adult life span are still limited
Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for <em>Schistosoma mansoni</em> and <em>S. haematobium</em> (Publications)
BACKGROUND: In sub-Saharan Africa the recommended strategy to control schistosomiasis is preventive chemotherapy. Emphasis is placed on school-aged children, but in high endemicity areas, preschool-ag
Formation of the circumsporozoite protein of <em>Plasmodium falciparum</em> in <em>Anopheles stephensi</em> (Publications)
The place and time of synthesis of the circumsporozoite protein of P. falciparum was analysed with a monoclonal antibody directed against the (NANP)3 repetitive epitope of the CS protein. By using an
An efficient system to generate monoclonal antibodies against membrane-associated proteins by immunisation with antigen-expressing mammalian cells (Publications)
ABSTRACT: BACKGROUND: The generation of monoclonal antibodies specific for protein antigens usually depends on purified recombinant protein for both immunisation and hybridoma screening. Purification