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1. Dipeptidyl enoates as potent rhodesain inhibitors that display a dual mode of action [Communication] (Publications)

   Dipeptidyl enoates as potent rhodesain inhibitors that display a dual mode of action [Communication]

   Relevance:

   Dipeptidyl enoates were prepared through a high-yielding two-step synthetic route. They have a dipeptidic structure with a 4-oxoenoate moiety as a warhead with multiple reactive sites. Dipeptidyl enoa

2. A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria (Publications)

   A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

   Relevance:

   Malaria is one of the most significant causes of childhood mortality, but disease control efforts are threatened by resistance of the Plasmodium parasite to current therapies. Continued progress in co

3. Civil registration and vital statistics: progress in the data revolution for counting and accountability (Publications)

   Civil registration and vital statistics: progress in the data revolution for counting and accountability

   Relevance:

   New momentum for civil registration and vital statistics (CRVS) is building, driven by the confluence of growing demands for accountability and results in health, improved equity, and rights-based app

4. Low coverage of central point vaccination against dog rabies in Bamako, Mali (Publications)

   Low coverage of central point vaccination against dog rabies in Bamako, Mali

   Relevance:

   Canine rabies remains an important public-health problem in Africa. Dog mass vaccination is the recommended method for rabies control and elimination. We report on the first small-scale mass dog vacci

5. Availability and satisfactoriness of latrines and hand washing stations in health facilities, and role in health seeking behavior of women: evidence... (Publications)

   Availability and satisfactoriness of latrines and hand washing stations in health facilities, and role in health seeking behavior of women: evidence from rural Pune district, India

   Relevance:

6. The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity (Publications)

   The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity

   Relevance:

   Lipid metabolism and receptor-mediated signaling are highly intertwined processes that cooperate to fulfill cellular functions and safeguard cellular homeostasis. Activation of Toll-like receptors (TL

7. Towards host-directed therapies for tuberculosis [Comment] (Publications)

   Towards host-directed therapies for tuberculosis [Comment]

   Relevance:

   The treatment of tuberculosis is based on combinations of drugs that directly target Mycobacterium tuberculosis. A new global initiative is now focusing on a complementary approach of developing adjun

8. Using metal ratios to detect emissions from municipal waste incinerators in ambient air pollution data, atmospheric environment (Publications)

   Using metal ratios to detect emissions from municipal waste incinerators in ambient air pollution data, atmospheric environment

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9. Chemical constituents from <em>Waltheria indica</em> exert <em>in vitro</em> activity against <em>Trypanosoma brucei</em> and <em>T. cruzi</em> (Publications)

   Chemical constituents from <em>Waltheria indica</em> exert <em>in vitro</em> activity against <em>Trypanosoma brucei</em> and <em>T. cruzi</em>

   Relevance:

   Six extracts from the roots and the aerial parts of Waltheria indica L. (Malvaceae) were screened for their in vitro antitrypanosomal activity towards Trypanosoma brucei brucei STIB 427 strain, Trypan

10. TB or not TB - persistent cough, fever and night sweats in a 46-year-old traveler returning from South America (Publications)

    TB or not TB - persistent cough, fever and night sweats in a 46-year-old traveler returning from South America

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